Despite rapid advances in modern medical technology and significant improvements in
survival rates of many cancers, pancreatic cancer is still a highly lethal gastrointestinal …

Metabolic pathways must be adapted to support cell processes required for transformation
and cancer progression. Amino acid metabolism is deregulated in many cancers, with …

The occurrence of obesity has increased across the whole world. Many epidemiological
studies have indicated that obesity strongly contributes to the development of cancer …

The extracellular matrix (ECM) is a network of different proteins and proteoglycans that
controls differentiation, migration, repair, survival, and development, and it seems that its …

At the moment, pancreatic cancer is among the deadliest gastrointestinal diseases, and
pancreatic cancer growth is a complex biological process that is based on different kinds of …

The tumor microenvironment (TME) is a biological system with sophisticated constituents. In
addition to tumor cells, tumor‐associated macrophages (TAMs) and microbiota are also …

Advanced cancer patients exhibit cachexia, a condition characterized by a significant
reduction in the body weight predominantly from loss of skeletal muscle and adipose tissue …

Pancreatic cancer is one of the most lethal malignancies. Recent studies indicated that
development of pancreatic cancer may be intimately connected with the microbiome. In this …

Obesity leads to many diseases including hypercholesterolemia, type-2 diabetes,
hypertension, cardiovascular disease, and cancer. It is the fastest-growing lethal disease in …

Background Excess adiposity is considered causally related to pancreatic cancer. While
most knowledge on the topic comes from studies on general and visceral adiposity, the role …