Hyaluronic a cid–doxorubicin nanoparticles for targeted treatment of colorectal cancer
DC Pan, V Krishnan, AK Salinas, J Kim… - Bioengineering & …, 2021 - Wiley Online Library
Colorectal cancer, common in both men and women, occurs when tumors form in the linings
of the colon. Common treatments of colorectal cancer include surgery, chemotherapy, and …
of the colon. Common treatments of colorectal cancer include surgery, chemotherapy, and …
[HTML][HTML] Calreticulin and integrin alpha dissociation induces anti-inflammatory programming in animal models of inflammatory bowel disease
Inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease, is a
chronic intestinal inflammatory condition initiated by integrins-mediated leukocyte adhesion …
chronic intestinal inflammatory condition initiated by integrins-mediated leukocyte adhesion …
[HTML][HTML] Deficiency in STAT1 signaling predisposes gut inflammation and prompts colorectal cancer development
S Leon-Cabrera, A Vázquez-Sandoval… - Cancers, 2018 - mdpi.com
Signal transducer and activator of transcription 1 (STAT1) is part of the Janus kinase
(JAK/STAT) signaling pathway that controls critical events in intestinal immune function …
(JAK/STAT) signaling pathway that controls critical events in intestinal immune function …
Dysplasia and cancer in inflammatory bowel disease
Inflammatory bowel disease (IBD) is associated with an increased risk of developing
dysplasia and cancer. 1–3 Dysplasia and colitis-associated cancer (CAC) develop via a …
dysplasia and cancer. 1–3 Dysplasia and colitis-associated cancer (CAC) develop via a …
miR-29a-5p/STAT3 positive feedback loop regulates TETs in colitis-associated colorectal cancer
A Wang, S Deng, X Chen, C Yu, Q Du… - Inflammatory bowel …, 2020 - academic.oup.com
Abstract Background Interleukin (IL)-6/signal transducers and activators of transcription 3
(STAT3) signaling plays an important role in the development of colitis-associated colorectal …
(STAT3) signaling plays an important role in the development of colitis-associated colorectal …
[HTML][HTML] Reduction of inflammation and colon injury by a Pennyroyal phenolic extract in experimental inflammatory bowel disease in mice
Purpose Little is known about the pharmacological effects of the phenolic compounds of
Pennyroyal (Mentha pulegium). This Mediterranean aromatic plant, used as a gastronomic …
Pennyroyal (Mentha pulegium). This Mediterranean aromatic plant, used as a gastronomic …
[HTML][HTML] Inula viscosa phenolic extract suppresses colon cancer cell proliferation and ulcerative colitis by modulating oxidative stress biomarkers
Inula viscosa is a perennial herbaceous plant native to the Mediterranean Basin, which is
used topically for the treatment of various diseases in folk medicine. This study aimed to …
used topically for the treatment of various diseases in folk medicine. This study aimed to …
Increased Genetic Instability and Accelerated Progression of Colitis-Associated Colorectal Cancer through Intestinal Epithelium–specific Deletion of Klf4
Krüppel-like factor 4 (KLF4), a zinc finger transcription factor, regulates homeostasis of the
intestinal epithelium. Previously, it was reported that KLF4 functions as a tumor suppressor …
intestinal epithelium. Previously, it was reported that KLF4 functions as a tumor suppressor …
[HTML][HTML] Dynamic bioenergetic alterations in colorectal adenomatous polyps and adenocarcinomas
WR Lin, JM Chiang, SN Lim, MY Su, TH Chen… - …, 2019 - thelancet.com
Background Energy metabolism in carcinogenesis is poorly understood. It is widely
accepted the majority of colorectal cancers (CRCs) arise from adenomatous polyps (APs) …
accepted the majority of colorectal cancers (CRCs) arise from adenomatous polyps (APs) …
[HTML][HTML] NF-kappa B expression in resected specimen of colonic cancer is higher compared to its expression in inflammatory bowel diseases and polyps
L Berkovich, M Gerber, A Katzav, D Kidron, S Avital - Scientific Reports, 2022 - nature.com
NF-Kappa B has a significant role in inflammatory processes as well as in colorectal cancer.
The aim of this study was to compare the expression of NF-kappa B in colonic …
The aim of this study was to compare the expression of NF-kappa B in colonic …