Autism spectrum disorder: neuropathology and animal models
M Varghese, N Keshav, S Jacot-Descombes… - Acta …, 2017 - Springer
Autism spectrum disorder (ASD) has a major impact on the development and social
integration of affected individuals and is the most heritable of psychiatric disorders. An …
integration of affected individuals and is the most heritable of psychiatric disorders. An …
miRNA dosage control in development and human disease
In mammals, miRNAs recognize target mRNAs via base pairing, which leads to a complex
'multiple-to-multiple'regulatory network. Previous studies have focused on the regulatory …
'multiple-to-multiple'regulatory network. Previous studies have focused on the regulatory …
Determining the role of microRNAs in psychiatric disorders
Recent studies have revealed that patients with psychiatric disorders have altered
microRNA (miRNA) expression profiles in the circulation and brain. Furthermore, animal …
microRNA (miRNA) expression profiles in the circulation and brain. Furthermore, animal …
[HTML][HTML] Hippocampal-prefrontal theta-gamma coupling during performance of a spatial working memory task
Cross-frequency coupling supports the organization of brain rhythms and is present during a
range of cognitive functions. However, little is known about whether and how long-range …
range of cognitive functions. However, little is known about whether and how long-range …
Exome sequencing supports a de novo mutational paradigm for schizophrenia
B Xu, JL Roos, P Dexheimer, B Boone, B Plummer… - Nature …, 2011 - nature.com
Despite its high heritability, a large fraction of individuals with schizophrenia do not have a
family history of the disease (sporadic cases). Here we examined the possibility that rare de …
family history of the disease (sporadic cases). Here we examined the possibility that rare de …
[HTML][HTML] A selective review of the excitatory-inhibitory imbalance in schizophrenia: underlying biology, genetics, microcircuits, and symptoms
Y Liu, P Ouyang, Y Zheng, L Mi, J Zhao… - Frontiers in cell and …, 2021 - frontiersin.org
Schizophrenia is a chronic disorder characterized by specific positive and negative primary
symptoms, social behavior disturbances and cognitive deficits (eg, impairment in working …
symptoms, social behavior disturbances and cognitive deficits (eg, impairment in working …
Molecular genetics of 22q11. 2 deletion syndrome
BE Morrow, DM McDonald‐McGinn… - American journal of …, 2018 - Wiley Online Library
The 22q11. 2 deletion syndrome (22q11. 2DS) is a congenital malformation and
neuropsychiatric disorder caused by meiotic chromosome rearrangements. One of the goals …
neuropsychiatric disorder caused by meiotic chromosome rearrangements. One of the goals …
[PDF][PDF] MicroRNAs shape the neuronal landscape
E McNeill, D Van Vactor - Neuron, 2012 - cell.com
The nervous system equips us with capability to adapt to many conditions and
circumstances. We rely on an armamentarium of intricately formed neural circuits for many of …
circumstances. We rely on an armamentarium of intricately formed neural circuits for many of …
MicroRNA as repressors of stress-induced anxiety: the case of amygdalar miR-34
S Haramati, I Navon, O Issler, G Ezra-Nevo… - Journal of …, 2011 - Soc Neuroscience
The etiology and pathophysiology of anxiety and mood disorders is linked to inappropriate
regulation of the central stress response. To determine whether microRNAs have a …
regulation of the central stress response. To determine whether microRNAs have a …
[PDF][PDF] Sequestration of DROSHA and DGCR8 by expanded CGG RNA repeats alters microRNA processing in fragile X-associated tremor/ataxia syndrome
Fragile X-associated tremor/ataxia syndrome (FXTAS) is an inherited neurodegenerative
disorder caused by the expansion of 55–200 CGG repeats in the 5′ UTR of FMR1. These …
disorder caused by the expansion of 55–200 CGG repeats in the 5′ UTR of FMR1. These …