Reports of the increasing incidence of male infertility paired with decreasing semen quality
have triggered studies on the effects of lifestyle and environmental factors on the male …

Obesity is considered a global health problem affecting more than a third of the population.
Complications of obesity include cardiovascular diseases, type 2 diabetes mellitus …

Orexins, or hypocretins, are excitatory neuropeptides involved in the regulation of feeding
behavior and the sleep and wakefulness states. Since their discovery, several lines of …

The orexin/hypocretin neuropeptide family has emerged as a focal point of neuroscientific
research following the discovery that this family plays a crucial role in a variety of …

The orexin peptides (orexin A, orexin B) and their receptors (orexin receptor type 1, orexin
receptor type 2) are involved in multiple physiological processes such as the regulation of …

Orexins are neuropeptides that activate the rhodopsin-like G protein-coupled receptors
OX1R and OX2R. The orexin system plays an important role in the regulation of the sleep …

The lateral hypothalamus is critical for the control of ingestive behavior and spontaneous
physical activity (SPA), as lesion or stimulation of this region alters these behaviors …

Obesity has become a global pandemic since the last few decades with prevalence in more
than one-third of the population in the United States. Another concurrent global health …

Interdisciplinary studies in the research fields of endocrinology and immunology show that
obesity-associated overnutrition leads to neuroinflammatory molecular changes, in …

Abstract Purpose of Review Spontaneous physical activity (SPA) is a physical activity not
motivated by a rewarding goal, such as that associated with food-seeking or wheel-running …