The effect of a biodegradable contraceptive capsule (Capronor) containing levonorgestrel on gonadotropin, estrogen, and progesterone levels
SJ Ory, CB Hammond, SG Yancy, RW Hendren… - American journal of …, 1983 - Elsevier
Eight ovulatory women participated in the preliminary evaluation of a new method of
contraception. The technique consisted of subdermal implantation of a biodegradable …
contraception. The technique consisted of subdermal implantation of a biodegradable …
Release rates of levonorgestrel from SilasticR capsules, homogeneous rods and covered rods in humans
DN Robertson, I Sivin, HA Nash, J Braun, J Dinh - Contraception, 1983 - Elsevier
Three forms of subdermal implants containing levonorgestrel are described. These are:
capsules, in which the powdered drug is sealed inside of lengths of Medical Grade Silastic …
capsules, in which the powdered drug is sealed inside of lengths of Medical Grade Silastic …
Clinical evaluation of injectable biodegradable contraceptive system
LR Beck, RA Ramos, CE Flowers Jr, GZ Lopez… - American journal of …, 1981 - Elsevier
A new long acting injectable contraceptive system was tested in 24 women. The system
consists of microspheres made of biodegradable d, l-polylactic acid in which micronized …
consists of microspheres made of biodegradable d, l-polylactic acid in which micronized …
Gamma irradiated micro system for long-term parenteral contraception: an alternative to synthetic polymers
S Puthli, P Vavia - European journal of pharmaceutical sciences, 2008 - Elsevier
An injectable system of levonorgestrel (LNG) was developed using biodegradable polymer
of natural origin. The parenteral system was optimized for particle size and higher drug …
of natural origin. The parenteral system was optimized for particle size and higher drug …
Formulation and performance characterization of radio-sterilized “progestin-only” microparticles intended for contraception
S Puthli, P Vavia - AAPS PharmSciTech, 2009 - Springer
The aim of this study was to formulate and characterize a microparticulate system of
progestin-only contraceptive. Another objective was to evaluate the effect of gamma radio …
progestin-only contraceptive. Another objective was to evaluate the effect of gamma radio …
Physiologically active polymers and macromolecular therapeutic systems
NA Plate, AY Vasil'ev - Polymer Science USSR, 1982 - Elsevier
Polymers with physiological activity and macromolecular therapeutic systems for the
controlled delivery of medicinals within the body are considered. The polymers may display …
controlled delivery of medicinals within the body are considered. The polymers may display …
The effect of different contraceptive treatments on the serum concentration of dehydroepiandrosterone sulfate
KL Klove, S Roy, RA Lobo - Contraception, 1984 - Elsevier
Twenty-six healthy, non-hirsute women had antecubital venous blood obtained before and
during treatment with various contraceptive steroids for the measurement of …
during treatment with various contraceptive steroids for the measurement of …
A new look at progestogens
K Fotherby - Clinics in Obstetrics and Gynaecology, 1984 - Elsevier
The large number of oestrogen-progestogen formulations available for contraceptive use
was markedly reduced in the late 1960s when many progestogens were withdrawn on …
was markedly reduced in the late 1960s when many progestogens were withdrawn on …
Contraception with long-acting subdermal implants. A five-year clinical trial with silastic covered rod implants containing levonorgestrel
DN Robertson, S Diaz, F Alvarez-Sanchez, P Holma… - Contraception, 1985 - Elsevier
A total of 189 women volunteered to accept subdermal implants for contraception. The
implants were “covered rods”, consisting of a core rod containing equal parts by weight of …
implants were “covered rods”, consisting of a core rod containing equal parts by weight of …
Fabrication, characterization and in vivo studies of biodegradable gamma sterilized injectable microparticles for contraception
SP Puthli, PR Vavia - Pharmaceutical development and …, 2009 - Taylor & Francis
A Levonorgestrel-loaded microparticulate system was developed with gelatin and bovine
serum albumin using triple emulsion technique coupled with chemical cross-linking thermal …
serum albumin using triple emulsion technique coupled with chemical cross-linking thermal …