[HTML][HTML] Activation of Nrf2/HO-1 signaling: An important molecular mechanism of herbal medicine in the treatment of atherosclerosis via the protection of vascular …

Q Zhang, J Liu, H Duan, R Li, W Peng, C Wu - Journal of advanced …, 2021 - Elsevier
Abstract Introduction Recently, Nrf2/HO-1 has received extensive attention as the main
regulatory pathway of intracellular defense against oxidative stress and is considered an …

Resveratrol: A double-edged sword in health benefits

B Salehi, AP Mishra, M Nigam, B Sener, M Kilic… - Biomedicines, 2018 - mdpi.com
Resveratrol (3, 5, 4′-trihydroxy-trans-stilbene) belongs to polyphenols' stilbenoids group,
possessing two phenol rings linked to each other by an ethylene bridge. This natural …

Stilbenes: Source plants, chemistry, biosynthesis, pharmacology, application and problems related to their clinical Application-A comprehensive review

T Teka, L Zhang, X Ge, Y Li, L Han, X Yan - Phytochemistry, 2022 - Elsevier
Stilbenes are some of the important phenolic compounds originating from plant families like
Vitaceae, Leguminaceae, Gnetaceae, and Dipterocarpaceae. Structurally, they have a C6 …

Natural products: An upcoming therapeutic approach to cancer

S Dutta, S Mahalanobish, S Saha, S Ghosh… - Food and Chemical …, 2019 - Elsevier
Cancer is one of the leading causes of death across the world. Different environmental and
anthropogenic factors initiate mutations in different functional genes of growth factors and …

[HTML][HTML] Grape berry secondary metabolites and their modulation by abiotic factors in a climate change scenario–a review

M Rienth, N Vigneron, P Darriet, C Sweetman… - Frontiers in Plant …, 2021 - frontiersin.org
Temperature, water, solar radiation, and atmospheric CO 2 concentration are the main
abiotic factors that are changing in the course of global warming. These abiotic factors …

Modulation of nitric oxide synthases by oxidized LDLs: role in vascular inflammation and atherosclerosis development

M Gliozzi, M Scicchitano, F Bosco, V Musolino… - International journal of …, 2019 - mdpi.com
The maintenance of physiological levels of nitric oxide (NO) produced by eNOS represents a
key element for vascular endothelial homeostasis. On the other hand, NO overproduction …

Phytochemicals in cancer treatment and cancer prevention—review on epidemiological data and clinical trials

A Rudzińska, P Juchaniuk, J Oberda, J Wiśniewska… - Nutrients, 2023 - mdpi.com
Phytochemicals are a non-nutritive substances that are present in plants and contribute
significantly to their flavor and color. These biologically active compounds are classified into …

Current perspectives of the applications of polyphenols and flavonoids in cancer therapy

X Montané, O Kowalczyk, B Reig-Vano, A Bajek… - Molecules, 2020 - mdpi.com
The development of anticancer therapies that involve natural drugs has undergone
exponential growth in recent years. Among the natural compounds that produce beneficial …

Chemistry, biosynthesis and pharmacology of viniferin: potential resveratrol-derived molecules for new drug discovery, development and therapy

S Fuloria, M Sekar, FS Khattulanuar, SH Gan… - Molecules, 2022 - mdpi.com
Viniferin is a resveratrol derivative. Resveratrol is the most prominent stilbenoid synthesized
by plants as a defense mechanism in response to microbial attack, toxins, infections or UV …

[HTML][HTML] Plants secondary metabolites as blood glucose-lowering molecules

MB Shehadeh, GARY Suaifan, AM Abu-Odeh - Molecules, 2021 - mdpi.com
Recently, significant advances in modern medicine and therapeutic agents have been
achieved. However, the search for effective antidiabetic drugs is continuous and …