The heart and brain have bi-directional influences on each other, including autonomic
regulation and hemodynamic connections. Heart rate variability (HRV) measures variation in …

This review summarizes recent evidence on how mid‐life hypertension,
hyperhomocysteinemia (HHcy) and blood pressure variability, as well as late‐life …

Background Resting heart rate (RHR) has been linked with an increased risk of dementia.
However, evidence characterizing the associations of RHR with different dementia subtypes …

Agitation in Alzheimer's disease is common and may be related to impaired emotion
regulation capacity. Heart rate variability, a proposed index of autonomic and emotion …

Background Developing a screening method for identifying individuals at higher risk of
elevated brain amyloid burden is important to reduce costs and burden to patients in clinical …

Cardiovascular diseases (CVD) and neurodegenerative disorders, such as Alzheimer's
disease (AD), are highly prevalent conditions in middle‐aged women that severely impair …

Background Population aging is a global public health issue involving increased prevalence
of age-related diseases, and concomitant burden on medical resources and the economy …

Background and aims Transportation noise is an environmental exposure with mounting
evidence of adverse health effects. Besides the increased risk of cardiovascular and …

The baroreflex is a powerful physiological mechanism for rapidly adjusting heart rate in
response to changes in blood pressure. Spontaneous baroreflex sensitivity (BRS) has been …

Many factors outside of cardiovascular health can impact the structure of white matter.
Identification of reliable and clinically meaningful biomarkers of the neural effects of systemic …