[HTML][HTML] Current therapeutic strategies for patients with hypopharyngeal carcinoma: oncologic and functional outcomes

A Bozec, G Poissonnet, O Dassonville… - Journal of Clinical …, 2023 - mdpi.com
Hypopharyngeal cancer is usually diagnosed at an advanced stage and is associated with a
high risk of recurrence and poor survival rates. Although they differ greatly in terms of …

[HTML][HTML] Circ_0058106 promotes proliferation, metastasis and EMT process by regulating Wnt2b/β-catenin/c-Myc pathway through miR-185-3p in hypopharyngeal …

C Li, W Li, S Cao, J Xu, Y Qian, X Pan, D Lei… - Cell death & …, 2021 - nature.com
Hypopharyngeal squamous cell carcinoma (HSCC) accounts 95% of hypopharyngeal
cancer, which is characterized by high early metastasis rate and poor prognosis. It is …

[HTML][HTML] Electrochemotherapy for head and neck cancers: possibilities and limitations

A Morozas, V Malyško-Ptašinskė, J Kulbacka… - Frontiers in …, 2024 - frontiersin.org
Head and neck cancer continues to be among the most prevalent types of cancer globally,
yet it can be managed with appropriate treatment approaches. Presently, chemotherapy and …

[HTML][HTML] Single-cell RNA sequencing reveals pro-invasive cancer-associated fibroblasts in hypopharyngeal squamous cell carcinoma

Z Cai, L Chen, S Chen, R Fang, X Chen… - Cell Communication and …, 2023 - Springer
Background Hypopharyngeal squamous cell carcinoma (HPSCC) has the worst prognosis
among all head-and-neck cancers, and treatment options are limited. Tumor …

RNA methyltransferase NSUN2 promotes hypopharyngeal squamous cell carcinoma proliferation and migration by enhancing TEAD1 expression in an m5C …

L Chen, J Ding, B Wang, X Chen, X Ying, Z Yu… - Experimental cell …, 2021 - Elsevier
RNA methyltransferase NSUN2 is involved in cell proliferation and invasion in a variety of
tumors. However, the expression, function, and mechanism of NSUN2 in hypopharyngeal …

Co-targeting PI3K/Akt and MAPK/ERK pathways leads to an enhanced antitumor effect on human hypopharyngeal squamous cell carcinoma

X Peng, Y Liu, S Zhu, X Peng, H Li, W Jiao… - Journal of cancer …, 2019 - Springer
Purpose The present study aims to determine whether co-targeting PI3K/Akt and MAPK/ERK
pathways in human hypopharyngeal squamous cell carcinoma (HSCC) is a potential …

[HTML][HTML] The effect of HPV DNA and p16 status on the prognosis of patients with hypopharyngeal carcinoma: a meta-analysis

J Shi, L Wang, N Yao, L Sun, W Hu, X Li, Y Yang… - BMC cancer, 2022 - Springer
Objective To evaluate whether the presence of human papillomavirus (HPV) DNA and p16
might be associated with better prognosis in patients with hypopharyngeal carcinoma …

[HTML][HTML] Hypopharyngeal cancer

O Sanders, S Pathak - StatPearls [Internet], 2022 - ncbi.nlm.nih.gov
Objectives: Summarize the risk factors for the formation of hypopharyngeal cancer. Describe
the frequent presentations of hypopharyngeal cancer. Review the diagnostic process and …

[HTML][HTML] RELA is required for CD271 expression and stem-like characteristics in hypopharyngeal cancer

A Nakazato, M Mochizuki, R Shibuya-Takahashi… - Scientific Reports, 2022 - nature.com
CD271 (also referred to as nerve growth factor receptor or p75NTR) is expressed on cancer
stem cells in hypopharyngeal cancer (HPC) and regulates cell proliferation. Because …

[HTML][HTML] CPT1A mediates chemoresistance in human hypopharyngeal squamous cell carcinoma via ATG16L1-dependent cellular autophagy

L Sun, X Wang, L Chen, Z Gao, S Xu, C Hu, G Fan… - Cell Insight, 2023 - Elsevier
Hypopharyngeal squamous cell carcinoma (HSCC) is a highly aggressive malignancy that
constitutes approximately 95% of all hypopharyngeal carcinomas, and it carries a poor …