Systemic maternal inflammation promotes ASD via IL-6 and IFN-γ
D Majerczyk, EG Ayad, KL Brewton, P Saing… - Bioscience …, 2022 - portlandpress.com
Autism spectrum disorder (ASD) is a neurological disorder that manifests during early
development, impacting individuals through their ways of communicating, social behaviors …
development, impacting individuals through their ways of communicating, social behaviors …
Pain in neuropsychiatry: Insights from animal models
Pain is the most common symptom reported in clinical practice, meaning that it is associated
with many pathologies as either the origin or a consequence of other illnesses. Furthermore …
with many pathologies as either the origin or a consequence of other illnesses. Furthermore …
[HTML][HTML] Aberrant IL-17 levels in rodent models of autism Spectrum disorder: a systematic review
AJ Thawley, LP Veneziani… - Frontiers in …, 2022 - frontiersin.org
Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental disorder
characterised by stereotyped behaviours, specific interests, and impaired communication …
characterised by stereotyped behaviours, specific interests, and impaired communication …
[HTML][HTML] The effects of Peripubertal THC exposure in neurodevelopmental rat models of psychopathology
M Di Bartolomeo, T Stark, S Di Martino… - International Journal of …, 2023 - mdpi.com
Adolescent exposure to cannabinoids as a postnatal environmental insult may increase the
risk of psychosis in subjects exposed to perinatal insult, as suggested by the two-hit …
risk of psychosis in subjects exposed to perinatal insult, as suggested by the two-hit …
Transcription factors in neurodevelopmental and associated psychiatric disorders: A potential convergence for genetic and environmental risk factors
J Santos‐Terra, I Deckmann… - International Journal …, 2021 - Wiley Online Library
Neurodevelopmental disorders (NDDs) are a heterogeneous and highly prevalent group of
psychiatric conditions marked by impairments in the nervous system. Their onset occurs …
psychiatric conditions marked by impairments in the nervous system. Their onset occurs …
[HTML][HTML] Emerging roles of T helper cells in non-infectious neuroinflammation: savior or sinner
CD4+ T cells, also known as T helper (Th) cells, contribute to the adaptive immunity both in
the periphery and in the central nervous system (CNS). At least seven subsets of Th cells …
the periphery and in the central nervous system (CNS). At least seven subsets of Th cells …
[HTML][HTML] Chemical modulators for targeting autism spectrum disorders: from bench to clinic
S Lim, S Lee - Molecules, 2022 - mdpi.com
Autism spectrum disorders (ASD) are neurodevelopmental disorders characterized by
diverse behavioral symptoms such as repetitive behaviors, social deficits, anxiety …
diverse behavioral symptoms such as repetitive behaviors, social deficits, anxiety …
Nuclear factor kappa B in autism spectrum disorder: a systematic review
X Liao, Y Li - Pharmacological Research, 2020 - Elsevier
Background The nuclear factor kappa B (NF-κB) is composed of a series of transcription
factors, which are involved in the expression of a plethora of target genes, many of these …
factors, which are involved in the expression of a plethora of target genes, many of these …
[HTML][HTML] Alleviation of cisplatin-induced neuropathic pain, neuronal apoptosis, and systemic inflammation in mice by rapamycin
M Alotaibi, F Al-Aqil, F Alqahtani, M Alanazi… - Frontiers in Aging …, 2022 - frontiersin.org
Platinum-based chemotherapeutic treatment of cancer patients is associated with
debilitating adverse effects. Several adverse effects have been well investigated, and can be …
debilitating adverse effects. Several adverse effects have been well investigated, and can be …
Inhibition of tyrosine kinase signaling by tyrphostin AG126 downregulates the IL-21/IL-21R and JAK/STAT pathway in the BTBR mouse model of autism
Autism spectrum disorder (ASD) comprises a broad range of neurodevelopmental disorders
that are associated with deficits in social interaction and communication. The tyrosine kinase …
that are associated with deficits in social interaction and communication. The tyrosine kinase …