Tumour necrosis factor antagonists: structure, function, and tuberculosis risks

RS Wallis - The Lancet infectious diseases, 2008 - thelancet.com
Our understanding of the infection risks presented by tumour necrosis factor (TNF)
antagonists has continued to evolve in the 10 years since these drugs were first introduced …

TNFα blockade in human diseases: an overview of efficacy and safety

J Lin, D Ziring, S Desai, S Kim, M Wong, Y Korin… - Clinical …, 2008 - Elsevier
Tumor necrosis factor-alpha (TNFα) antagonists including antibodies and soluble receptors
have shown remarkable efficacy in various immune-mediated inflammatory diseases (IMID) …

Sarcoidosis and uveitis

Y Jamilloux, L Kodjikian, C Broussolle, P Sève - Autoimmunity reviews, 2014 - Elsevier
Abstract Uveitis is a frequent (20–50%) and early feature of sarcoidosis. Typical sarcoid
uveitis presents with mutton-fat keratic precipitates, iris nodules, and anterior and posterior …

Sarcoid-like granulomatosis in patients treated with tumor necrosis factor blockers: 10 cases

CI Daïen, A Monnier, P Claudepierre… - …, 2009 - academic.oup.com
Objective. TNF blockers have been recently evaluated for treating refractory sarcoidosis and
could be efficient. However, several cases of sarcoidosis have been diagnosed during anti …

Sarcoidosis—scientific progress and clinical challenges

ES Chen, DR Moller - Nature Reviews Rheumatology, 2011 - nature.com
Sarcoidosis is an uncommon systemic inflammatory disorder characterized by noncaseating
granulomatous inflammation that most commonly affects the lungs, intrathoracic lymph …

New treatment strategies for pulmonary sarcoidosis: antimetabolites, biological drugs, and other treatment approaches

RP Baughman, JC Grutters - The Lancet Respiratory Medicine, 2015 - thelancet.com
About half of patients with sarcoidosis will need systemic therapy for their disease. Oral
glucocorticoids are the standard first-line treatment for sarcoidosis. With time, patients might …

Long‐term corticosteroid‐sparing immunosuppression for cardiac sarcoidosis

DG Rosenthal, P Parwani, TO Murray… - Journal of the …, 2019 - Am Heart Assoc
Background Long‐term corticosteroid therapy is the standard of care for treatment of cardiac
sarcoidosis (CS). The efficacy of long‐term corticosteroid‐sparing immunosuppression in …

The pathogenesis of pulmonary sarcoidosis and implications for treatment

KC Patterson, ES Chen - Chest, 2018 - Elsevier
Thoracic sarcoidosis is the most common form of sarcoidosis, encompassing a
heterogeneous group of patients with a wide range of clinical features and associated …

Refractory sarcoidosis: a review

T El Jammal, Y Jamilloux… - … and clinical risk …, 2020 - Taylor & Francis
Sarcoidosis is a multi-system disease of unknown etiology characterized by granuloma
formation in various organs (especially lung and mediastinohilar lymph nodes). In more than …

Pulmonary fibrosis in sarcoidosis. Clinical features and outcomes

KC Patterson, ME Strek - Annals of the American Thoracic Society, 2013 - atsjournals.org
Sarcoidosis is a systemic inflammatory disease with a predilection for the respiratory system.
Although most patients enter remission and have good long-term outcomes, up to 20 …