BACKGROUND Infertility and pregnancy loss are longstanding problems. Successful
fertilization and high-quality embryos are prerequisites for an ongoing pregnancy. Studies …

The initiation of prostate cancer has been long associated with DNA copy-number
alterations, the loss of specific chromosomal regions and gene fusions, and driver mutations …

Intestinal inflammation induced by heat stress is an important factor restricting the healthy
growth of broilers. The aim of this study was to evaluate the effect of chicken embryo thermal …

During embryo implantation, blastocyst interacts with the receptivity endometrium and the
endometrial epithelium secretes nurturing fluid to support embryonic development …

The impact of omega-3 nutritional manipulation on semen cryosurvival and quality post
thawing is controversial. Our aim was to examine how feeding bulls with omega-3 …

Influenza A virus (IAV) is a leading cause of human respiratory infections and poses a major
public health concern. IAV replication can affect the expression of DNA methyltransferases …

DNA methylation can be considered the most prominent in controlling the gene expression
responsible for the balance between cell proliferation and cell death. In this study, we aimed …

The effects of culture media on DNA methylation process, which is one of the epigenetic
mechanisms, have not been clearly elucidated although it is known that in vitro culture …

Epigenetic mechanisms are one of the essential regulators of gene expression which do not
involve altering the primary nucleotide sequence. DNA methylation is considered among the …

DNA 甲基化(DNA methylation) 是一种动态, 可逆并可以遗传的表观遗传修饰模式,
主要发生在哺乳动物原始生殖细胞和早期胚胎发育过程中, 能够通过高动态和协同的核酶网络 …