Acidity‐Triggered Transformable Polypeptide Self‐Assembly to Initiate Tumor‐Specific Biomineralization

Y Liu, Z Jiang, S Tong, Y Sun, Y Zhang… - Advanced …, 2023 - Wiley Online Library
Biomineralization is a normal physiological process that includes nucleation, crystal growth,
phase transformation, and orientation evolution. Notably, artificially induced …

Risk factors for hepatic toxicity of high-dose methotrexate in patients with osteosarcoma

K Abe, A Maeda-Minami, T Ishizu, S Iwata… - Anticancer …, 2022 - ar.iiarjournals.org
Background/Aim: High-dose methotrexate (HD-MTX) is widely used to treat osteosarcoma.
However, some patients develop hepatic toxicity, leading to dose modification and delays in …

[HTML][HTML] BNTA alleviates inflammatory osteolysis by the SOD mediated anti-oxidation and anti-inflammation effect on inhibiting osteoclastogenesis

H Wang, X Cao, J Guo, X Yang, X Sun, Z Fu… - Frontiers in …, 2022 - frontiersin.org
Abnormal activation and overproliferation of osteoclast in inflammatory bone diseases lead
to osteolysis and bone mass loss. Although current pharmacological treatments have made …

A systematic review of the expression, signalling and function of P2 receptors in primary bone cancer

L Tattersall, DC Gagui, VL Tippett… - Frontiers in …, 2022 - eprints.whiterose.ac.uk
Primary bone cancers are rare malignant diseases with significant morbidity and mortality.
The treatment regimen relies on a combination of surgery (often involving amputation) …

[HTML][HTML] MiR-190a regulates milk protein biosynthesis through the mTOR and JAK2–STAT5 signaling pathways by targeting PTHLH in buffalo mammary epithelial …

X Fan, L Qiu, L Huang, W Zhu, Y Zhang… - Journal of Functional …, 2023 - Elsevier
Milk protein is a key quality indicator of milk, so elucidating its synthesis mechanism has
been the focus of research in recent years. Studies have shown that both miRNAs and …

[PDF][PDF] 甲状旁腺激素1 型受体对骨肉瘤细胞炎症因子和血管生成的影响及其机制研究

李盛龙, 刘霏, 郑珂, 王巍, 裴祎, 王爽 - 中华解剖与临床杂志, 2022 - cjac.com.cn
目的探讨甲状旁腺激素1 型受体(PTHR1) 对骨肉瘤细胞炎症因子和血管生成的影响及其机制.
方法培养骨肉瘤MG63 细胞, 分为PTHR1 阴性对照组(si-NC 组) 和PTHR1 小干扰RNA 组(si …

Gene expression profile comparison of primary and pulmonary metastatic lesions in a dog with appendicular osteosarcoma and hypertrophic osteopathy

K Kitagawa, J Dryfhout, AI Engleberg, YT Yang… - 2024 - researchsquare.com
Hypertrophic osteopathy (HO) is a paraneoplastic syndrome, and the most notable cause in
dogs is pulmonary metastatic osteosarcoma (OSA). Although many molecular factors in …