[HTML][HTML] Aqueous outflow-A continuum from trabecular meshwork to episcleral veins
T Carreon, E van der Merwe, RL Fellman… - Progress in retinal and …, 2017 - Elsevier
In glaucoma, lowered intraocular pressure (IOP) confers neuroprotection. Elevated IOP
characterizes glaucoma and arises from impaired aqueous humor (AH) outflow. Increased …
characterizes glaucoma and arises from impaired aqueous humor (AH) outflow. Increased …
[HTML][HTML] Aqueous outflow regulation–21st century concepts
M Johnstone, C Xin, J Tan, E Martin, J Wen… - Progress in retinal and …, 2021 - Elsevier
We propose an integrated model of aqueous outflow control that employs a pump-conduit
system in this article. Our model exploits accepted physiologic regulatory mechanisms such …
system in this article. Our model exploits accepted physiologic regulatory mechanisms such …
Developing an experimental-computational workflow to study the biomechanics of the human conventional aqueous outflow pathway
The aqueous humor actively interacts with the trabecular meshwork (TM), juxtacanalicular
tissue (JCT), and Schlemm's canal (SC) through a dynamic fluid-structure interaction (FSI) …
tissue (JCT), and Schlemm's canal (SC) through a dynamic fluid-structure interaction (FSI) …
[HTML][HTML] Estimating human trabecular meshwork stiffness by numerical modeling and advanced OCT imaging
Purpose: The purpose of this study was to estimate human trabecular meshwork (hTM)
stiffness, thought to be elevated in glaucoma, using a novel indirect approach, and to …
stiffness, thought to be elevated in glaucoma, using a novel indirect approach, and to …
Aqueous angiography in living nonhuman primates shows segmental, pulsatile, and dynamic angiographic aqueous humor outflow
Purpose To evaluate the feasibility of safely performing aqueous angiography in intact eyes
of living nonhuman primates (NHPs) for evaluating aqueous humor outflow and segmental …
of living nonhuman primates (NHPs) for evaluating aqueous humor outflow and segmental …
Biomechanics of human trabecular meshwork in healthy and glaucoma eyes via dynamic Schlemm's canal pressurization
Background and objective The trabecular meshwork (TM) consists of extracellular matrix
(ECM) with embedded collagen and elastin fibers providing its mechanical support. TM …
(ECM) with embedded collagen and elastin fibers providing its mechanical support. TM …
[HTML][HTML] Aqueous outflow regulation: Optical coherence tomography implicates pressure-dependent tissue motion
Glaucoma is a leading cause of blindness worldwide and results from damage to the optic
nerve. Currently, intraocular pressure is the only treatable risk factor. Changes in aqueous …
nerve. Currently, intraocular pressure is the only treatable risk factor. Changes in aqueous …
Structural and functional imaging of aqueous humour outflow: a review
AS Huang, BA Francis… - Clinical & experimental …, 2018 - Wiley Online Library
Maintaining healthy aqueous humour outflow (AHO) is important for intraocular cellular
health and stable vision. Impairment of AHO can lead to increased intraocular pressure …
health and stable vision. Impairment of AHO can lead to increased intraocular pressure …
Viscoelastic biomechanical properties of the conventional aqueous outflow pathway tissues in healthy and glaucoma human eyes
Background: Although the tissues comprising the ocular conventional outflow pathway have
shown strong viscoelastic mechanical response to aqueous humor pressure dynamics, the …
shown strong viscoelastic mechanical response to aqueous humor pressure dynamics, the …
How many aqueous humor outflow pathways are there?
The aqueous humor (AH) outflow pathways definition is still matter of intense debate. To
date, the differentiation between conventional (trabecular meshwork) and unconventional …
date, the differentiation between conventional (trabecular meshwork) and unconventional …