[HTML][HTML] The Challenge of overcoming antibiotic resistance in carbapenem-resistant Gram-negative bacteria:“Attack on Titan”

G Mancuso, S De Gaetano, A Midiri, S Zummo… - Microorganisms, 2023 - mdpi.com
The global burden of bacterial resistance remains one of the most serious public health
concerns. Infections caused by multidrug-resistant (MDR) bacteria in critically ill patients …

ESKAPE in China: epidemiology and characteristics of antibiotic resistance

Q Luo, P Lu, Y Chen, P Shen, B Zheng, J Ji… - Emerging Microbes & …, 2024 - Taylor & Francis
The escalation of antibiotic resistance and the diminishing antimicrobial pipeline have
emerged as significant threats to public health. The ESKAPE pathogens–Enterococcus …

[HTML][HTML] Trends in antibiotic resistance of nosocomial and community-acquired infections in Italy

P Cerini, FR Meduri, F Tomassetti, I Polidori… - Antibiotics, 2023 - mdpi.com
The World Health Organization has recently identified three categories of pathogens,
namely: critical, high, and medium priority, according to the need for new antibiotics. Critical …

[HTML][HTML] Selection and validation of reference genes suitable for gene expression analysis by Reverse Transcription Quantitative real-time PCR in Acinetobacter …

PAA de Oliveira, J Baboghlian, COA Ramos… - Scientific Reports, 2024 - nature.com
Acinetobacter baumannii is a Gram-negative bacterium considered an emerging multi-drug-
resistant pathogen. Furthermore, this bacterium can survive in extreme environmental …

Gut microbiota in parasite-transmitting gastropods

P Li, J Hong, Z Yuan, Y Huang, M Wu… - Infectious Diseases of …, 2023 - mednexus.org
Background Gastropoda, the largest class within the phylum Mollusca, houses diverse gut
microbiota, and some gastropods serve as intermediate hosts for parasites. Studies have …

[HTML][HTML] Decoding the resistome, virulome and mobilome of clinical versus aquatic Acinetobacter baumannii in southern Romania

I Gheorghe-Barbu, M Surleac, IC Barbu, S Paraschiv… - Heliyon, 2024 - cell.com
Acinetobacter baumannii, a notorious opportunistic pathogen, presents a formidable
challenge in both clinical and environmental fields due to its resilience and ability to acquire …

[HTML][HTML] Appelmans protocol–A directed in vitro evolution enables induction and recombination of prophages with expanded host range

TN Vu, JR Clark, E Jang, R D'Souza, NA Pinto, S Yoo… - Virus Research, 2024 - Elsevier
Infections caused by carbapenem-resistant Acinetobacter baumannii (CRAB) present
significant healthcare challenges due to limited treatment options. Bacteriophage (phage) …

[HTML][HTML] Prevalence of Carbapenemases in Carbapenem-Resistant Acinetobacter baumannii Isolates from the Kingdom of Bahrain

N Al-Rashed, KM Bindayna, M Shahid, NK Saeed… - Antibiotics, 2023 - mdpi.com
Background: Acinetobacter baumannii is regarded as a significant cause of death in
hospitals. The WHO recently added carbapenem-resistant Acinetobacter baumannii (CRAB) …

[HTML][HTML] A fresh pH-responsive imipenem-loaded nanocarrier against Acinetobacter baumannii with a synergetic effect

S Gui, X Li, M Feng, H Liu, L Huang… - Frontiers in Bioengineering …, 2023 - frontiersin.org
In recent years, the treatment of Acinetobacter baumannii infections has become a pressing
clinical challenge due to its increasing incidence and its serious pathogenic risk. The …

[HTML][HTML] Performance of the Disc Diffusion Method, MTS Gradient Tests and Two Commercially Available Microdilution Tests for the Determination of Cefiderocol …

K Jeannot, S Gaillot, P Triponney, S Portets, V Pourchet… - Microorganisms, 2023 - mdpi.com
Cefiderocol is a siderophore-conjugated cephalosporin with potent activity against multidrug-
resistant Gram-negative pathogens including Acinetobacter baumannii. The aim of this study …