Vascular dementia (VaD) is the second most common form of dementia after Alzheimer's
disease (AD); where Alzheimer's accounts for 60–70% of cases of dementia and VaD …

There are numerous theories of aging, a process which still seems inevitable. Aging leads to
cancer and multi-systemic disorders as well as chronic diseases. Decline in age-associated …

The term neurovascular unit (NVU) describes the structural and functional liaison between
specialized brain endothelium, glial and mural cells, and neurons. Within the NVU, the blood …

Age is associated with increased risk for several disorders including dementias,
cardiovascular disease, atherosclerosis, obesity, and diabetes. Age is also associated with …

Vascular dementia (VaD) is the second leading form of memory loss after Alzheimer's
disease (AD). Currently, there is no cure available. The etiology, pathophysiology and …

In the last years, there has been a significant growth in the literature exploring the
pathophysiology of vascular cognitive impairment (VCI). As an “umbrella term” …

Background Although cerebral white matter lesions (WMLs) are considered as a risk factor
for vascular dementia, data on their impact on cerebral hemodynamics are scarce. We test …

Introduction: Late-life depression is a well-known risk factor for future dementia. Increasing
evidences also show a link between cerebral hypoperfusion and neurodegeneration …

Background Subcortical ischemic vascular dementia (SIVD) is very common among the
older people, but has no approved treatment. Preclinical trials show that remote ischemic …

Cognitive impairment (CI) is a major health concern in aging populations. It impairs patients'
independent life and may progress to dementia. Vascular cognitive impairment (VCI) …