Single-cell patterning: a new frontier in bioengineering

R Gayathri, S Kar, M Nagai, FG Tseng… - Materials Today …, 2022 - Elsevier
Single-cell patterning technologies are rapidly evolving, where single cells are positioned in
spatially distinct areas, thus providing a platform for several biological and biomedical …

3D printed biohybrid microsystems

VY Prinz, KB Fritzler - Advanced Materials Technologies, 2023 - Wiley Online Library
This review is devoted to the role of 3D printing in the development of a new high‐tech field,
smart biohybrid microsystems. The motivation behind the development of this field is the …

Drosophila CASK regulates brain size and neuronal morphogenesis, providing a genetic model of postnatal microcephaly suitable for drug discovery

JA Tello, L Jiang, Y Zohar, LL Restifo - Neural Development, 2023 - Springer
Background CASK-related neurodevelopmental disorders are untreatable. Affected children
show variable severity, with microcephaly, intellectual disability (ID), and short stature as …

Portrait of intense communications within microfluidic neural networks

V Dupuit, A Briançon-Marjollet, C Delacour - Scientific Reports, 2023 - nature.com
In vitro model networks could provide cellular models of physiological relevance to
reproduce and investigate the basic function of neural circuits on a chip in the laboratory …

Microfabrication and lab-on-a-chip devices promote in vitro modeling of neural interfaces for neuroscience researches and preclinical applications

Y Liu, X Yao, C Fan, G Zhang, X Luo, Y Qian - Biofabrication, 2023 - iopscience.iop.org
Neural tissues react to injuries through the orchestration of cellular reprogramming,
generating specialized cells and activating gene expression that helps with tissue …

Integrated Microfluidics for Single‐Cell Separation and On‐Chip Analysis: Novel Applications and Recent Advances

H Kutluk, M Viefhues, I Constantinou - Small Science, 2024 - Wiley Online Library
From deciphering infection and disease mechanisms to identifying novel biomarkers and
personalizing treatments, the characteristics of individual cells can provide significant …

Customizable Microfluidic Devices: Progress, Constraints, and Future Advances

AAA Aljabali, MA Obeid, V Mishra… - Current Drug …, 2024 - ingentaconnect.com
The field of microfluidics encompasses the study of fluid behavior within micro-channels and
the development of miniature systems featuring internal compartments or passageways …

Flexible neural probes: a review of the current advantages, drawbacks, and future demands

S Pimenta, JR Freitas, JH Correia - Journal of Zhejiang University …, 2024 - Springer
Brain diseases affect millions of people and have a huge social and economic impact. The
use of neural probes for studies in animals has been the main approach to increasing …

Cultivation and Imaging of S. latissima Embryo Monolayered Cell Sheets Inside Microfluidic Devices

T Clerc, S Boscq, R Attia, GS Kaminski Schierle… - Bioengineering, 2022 - mdpi.com
The culturing and investigation of individual marine specimens in lab environments is crucial
to further our understanding of this highly complex ecosystem. However, the obtained results …

Proteomics mining of cancer hallmarks on a single‐cell resolution

M Li, J Zuo, K Yang, P Wang… - Mass Spectrometry …, 2023 - Wiley Online Library
Dysregulated proteome is an essential contributor in carcinogenesis. Protein fluctuations
fuel the progression of malignant transformation, such as uncontrolled proliferation …