Deep Learning Models Compared to Experimental Variability for the Prediction of CYP3A4 Time-Dependent Inhibition

A Fluetsch, M Trunzer, G Gerebtzoff… - Chemical research in …, 2024 - ACS Publications
Most drugs are mainly metabolized by cytochrome P450 (CYP450), which can lead to drug–
drug interactions (DDI). Specifically, time-dependent inhibition (TDI) of CYP3A4 isoenzyme …

Deep Learning Models Compared to Experimental Variability for the Prediction of CYP3A4 Time-Dependent Inhibition.

A Fluetsch, M Trunzer, G Gerebtzoff… - Chemical Research …, 2024 - europepmc.org
Most drugs are mainly metabolized by cytochrome P450 (CYP450), which can lead to drug-
drug interactions (DDI). Specifically, time-dependent inhibition (TDI) of CYP3A4 isoenzyme …

Deep Learning Models Compared to Experimental Variability for the Prediction of CYP3A4 Time-Dependent Inhibition

A Fluetsch, M Trunzer, G Gerebtzoff… - Chemical research …, 2024 - pubmed.ncbi.nlm.nih.gov
Most drugs are mainly metabolized by cytochrome P450 (CYP450), which can lead to drug-
drug interactions (DDI). Specifically, time-dependent inhibition (TDI) of CYP3A4 isoenzyme …

Deep Learning Models Compared to Experimental Variability for the Prediction of CYP3A4 Time-Dependent Inhibition.

A Fluetsch, M Trunzer, G Gerebtzoff… - Chemical research in …, 2024 - oak.novartis.com
Most drugs are mainly metabolized by cytochrome P450 (CYP450), which can lead to drug-
drug interactions (DDI). Specifically, time-dependent inhibition (TDI) of CYP3A4 isoenzyme …

Deep Learning Models Compared to Experimental Variability for the Prediction of CYP3A4 Time-Dependent Inhibition.

A Fluetsch, M Trunzer, G Gerebtzoff… - Chemical research in …, 2024 - oak.novartis.com
Most drugs are mainly metabolized by cytochrome P450 (CYP450), which can lead to drug-
drug interactions (DDI). Specifically, time-dependent inhibition (TDI) of CYP3A4 isoenzyme …