Lead optimization studies on FimH antagonists: discovery of potent and orally bioavailable ortho-substituted biphenyl mannosides

Z Han, JS Pinkner, B Ford, E Chorell… - Journal of medicinal …, 2012 - ACS Publications
Herein, we describe the X-ray structure-based design and optimization of biaryl mannoside
FimH inhibitors. Diverse modifications to the biaryl ring to improve druglike physical and …
被引用次数：161 相关文章

Lead optimization studies on FimH antagonists: discovery of potent and orally bioavailable ortho-substituted biphenyl mannosides

Z Han, JS Pinkner, B Ford, E Chorell… - Journal of …, 2012 - pubmed.ncbi.nlm.nih.gov
Herein, we describe the X-ray structure-based design and optimization of biaryl mannoside
FimH inhibitors. Diverse modifications to the biaryl ring to improve druglike physical and …
[PDF] academia.edu

[PDF][PDF] Lead Optimization Studies on FimH Antagonists: Discovery of Potent and Orally Bioavailable Ortho-substituted Biphenyl Mannosides

Z Han, JS Pinkner, B Ford, E Chorell, JM Crowley… - J Med Chem, 2012 - academia.edu
Herein, we describe the X-ray structure-based design and optimization of biaryl mannoside
FimH inhibitors. Diverse modifications to the biaryl ring to improve drug-like physical and …

[引用][C] Lead Optimization Studies on FimH Antagonists: Discovery of Potent and Orally Bioavailable Ortho-Substituted Biphenyl Mannosides

Z Han, JS Pinkner, B Ford, E Chorell… - Journal of Medicinal …, 2012 - cir.nii.ac.jp
Lead Optimization Studies on FimH Antagonists: Discovery of Potent and Orally Bioavailable
Ortho-Substituted Biphenyl Mannosides | CiNii Research CiNii 国立情報学研究所 学術情報 …

Lead optimization studies on FimH antagonists: discovery of potent and orally bioavailable ortho-substituted biphenyl mannosides.

Z Han, JS Pinkner, B Ford, E Chorell… - Journal of Medicinal …, 2012 - europepmc.org
Herein, we describe the X-ray structure-based design and optimization of biaryl mannoside
FimH inhibitors. Diverse modifications to the biaryl ring to improve drug-like physical and …

Lead Optimization Studies on FimH Antagonists: Discovery of Potent and Orally Bioavailable Ortho-Substituted Biphenyl Mannosides

Z Han, JW Janetka, JS Pinkner, B Ford… - Journal of Medicinal …, 2012 - hero.epa.gov
Herein, we describe the X-ray structure-based design and optimization of biaryl mannoside
FimH inhibitors. Diverse modifications to the biaryl ring to improve druglike physical and …
[HTML] nih.gov

[HTML][HTML] Lead Optimization Studies on FimH Antagonists: Discovery of Potent and Orally Bioavailable Ortho-substituted Biphenyl Mannosides

Z Han, JS Pinkner, B Ford, E Chorell… - Journal of Medicinal …, 2012 - ncbi.nlm.nih.gov
Herein, we describe the X-ray structure-based design and optimization of biaryl mannoside
FimH inhibitors. Diverse modifications to the biaryl ring to improve drug-like physical and …

Lead optimization studies on FimH antagonists: discovery of potent and orally bioavailable ortho-substituted biphenyl mannosides

Z Han, JS Pinkner, B Ford, E Chorell… - Journal of medicinal …, 2012 - iro.uiowa.edu
Herein, we describe the X-ray structure-based design and optimization of biaryl mannoside
FimH inhibitors. Diverse modifications to the biaryl ring to improve druglike physical and …

Lead optimization studies on FimH antagonists: Discovery of potent and orally bioavailable ortho-substituted biphenyl mannosides

Z Han, JS Pinkner, B Ford, E Chorell… - Journal of Medicinal …, 2012 - profiles.wustl.edu
Herein, we describe the X-ray structure-based design and optimization of biaryl mannoside
FimH inhibitors. Diverse modifications to the biaryl ring to improve druglike physical and …
[PDF] academia.edu

[PDF][PDF] Lead Optimization Studies on FimH Antagonists: Discovery of Potent and Orally Bioavailable Ortho-substituted Biphenyl Mannosides

Z Han, JS Pinkner, B Ford, E Chorell, JM Crowley… - J Med Chem, 2012 - academia.edu
Herein, we describe the X-ray structure-based design and optimization of biaryl mannoside
FimH inhibitors. Diverse modifications to the biaryl ring to improve drug-like physical and …