Isochromosomes are mirror-imaged chromosomes with simultaneous duplication and
deletion of genetic material which may contain two centromeres to create isodicentric …

Chromosomal aberrations, such as dicentric or isochromosomes, are prevalent in cancer
and developmental syndromes, yet mechanisms promoting their origin remain elusive. Here …

Isochromosomes are mirror-imaged chromosomes with simultaneous duplication and
deletion of genetic material which may contain two centromeres to create isodicentric …

Isochromosomes are mirror-imaged chromosomes with simultaneous duplication and
deletion of genetic material which may contain two centromeres to create isodicentric …

26 Factors governing the faithful replication of chromosomes are essential for cellular and
genomic integrity. 27 While a variety of mechanisms to manage breaks and promote repair …

Results Deletion of SETD2 Leads to Bridging and Lagging Chromosomes in Mitosis. To
quantify the frequency of chromosome missegregation following Setd2 loss, mouse …

Results Deletion of SETD2 Leads to Bridging and Lagging Chromosomes in Mitosis. To
quantify the frequency of chromosome missegregation following Setd2 loss, mouse …

Factors governing the faithful replication of chromosomes are essential for cellular and
genomic integrity. While a variety of mechanisms to manage breaks and promote repair of …

Chromosome mis-segregation during cell division occurs in diverse tumor types, promoting
aneuploidy and intratumoral genetic heterogeneity. While the mechanisms that govern …

Isochromosomes are mirror-imaged chromosomes with simultaneous duplication and
deletion of genetic material which may contain two centromeres to create isodicentric …