MEK inhibition induces MYOG and remodels super-enhancers in RAS-driven rhabdomyosarcoma

ME Yohe, BE Gryder, JF Shern, YK Song… - Science translational …, 2018 - science.org
The RAS isoforms are frequently mutated in many types of human cancers, including
PAX3/PAX7 fusion-negative rhabdomyosarcoma. Pediatric RMS arises from skeletal muscle …

MEK inhibition induces MYOG and remodels super-enhancers in RAS-driven rhabdomyosarcoma.

ME Yohe, BE Gryder, JF Shern… - Science …, 2018 - search.ebscohost.com
MEK inhibition decreases cell viability and induces differentiation in RAS-driven
rhabdomyosarcoma via an epigenetic mechanism. Muscling in on RAS …

MEK inhibition induces MYOG and remodels super-enhancers in RAS-driven rhabdomyosarcoma.

ME Yohe, BE Gryder, JF Shern, YK Song… - Science Translational …, 2018 - europepmc.org
The RAS isoforms are frequently mutated in many types of human cancers, including
PAX3/PAX7 fusion-negative rhabdomyosarcoma. Pediatric RMS arises from skeletal muscle …

[PDF][PDF] MEK inhibition induces MYOG and remodels super-enhancers in RAS-driven rhabdomyosarcoma

ME Yohe, BE Gryder, JF Shern, YK Song, HC Chou… - 2018 - researchgate.net
The RAS isoforms are frequently mutated in many types of human cancers, including
PAX3/PAX7 fusion-negative rhabdomyosarcoma. Pediatric RMS arises from skeletal muscle …

MEK inhibition induces MYOG and remodels super-enhancers in RAS-driven rhabdomyosarcoma

ME Yohe, BE Gryder, JF Shern… - Science …, 2018 - pubmed.ncbi.nlm.nih.gov
The RAS isoforms are frequently mutated in many types of human cancers, including
PAX3/PAX7 fusion-negative rhabdomyosarcoma. Pediatric RMS arises from skeletal muscle …

[HTML][HTML] MEK inhibition induces MYOG and remodels super-enhancers in RAS-driven rhabdomyosarcoma

ME Yohe, BE Gryder, JF Shern, YK Song… - Science translational …, 2018 - ncbi.nlm.nih.gov
The RAS isoforms are frequently mutated in many types of human cancers, including
PAX3/PAX7 fusion-negative rhabdomyosarcoma. Pediatric RMS arises from skeletal muscle …