In vitro and in vivo characterization of the estrogen dependent human breast cancer cell line, MCF-7, over-expressing cyclooxygenase-2

JR Prosperi - 2006 - rave.ohiolink.edu
The hypothesis for this dissertation is that cyclooxygenase-2 (Cox-2) and its product
prostaglandin E2 (PGE2) directly regulate proliferation, invasion, angiogenesis, aromatase …

[PDF][PDF] IN VITRO AND IN VIVO CHARACTERIZATION OF THE ESTROGEN-DEPENDENT HUMAN BREAST CANCER CELL LINE, MCF-7, OVER-EXPRESSING …

JR Prosperi - 2006 - etd.ohiolink.edu
Based on studies demonstrating the over-expression of Cox-2 in invasive human breast
cancer, the objective of the current study was to elucidate the role of human cyclooxygenase …