Id1, Spp1 and Pak3 are biomarkers of Smad4 and TGF-β1 dependency in conditional intestinal adenoma, organoids and colorectal cancer.
M Surakhy, J Matheson, D Barnes, E Carter, J Hughes… - bioRxiv, 2024 - biorxiv.org
The evolutionarily conserved TGF-β signalling pathway suppresses cell growth, yet loss of
function results in cancer phenotypes. Here, we evaluate loss of the TGF-β pathway signal …
function results in cancer phenotypes. Here, we evaluate loss of the TGF-β pathway signal …
Id1,Spp1andPak3are biomarkers ofSmad4and TGF-β1 dependency in conditional intestinal adenoma, organoids and colorectal cancer.
M Surakhy, J Matheson, D Barnes, E Carter, J Hughes… - 2024 - europepmc.org
The evolutionarily conserved TGF-β signalling pathway suppresses cell growth, yet loss of
function results in cancer phenotypes. Here, we evaluate loss of the TGF-β pathway signal …
function results in cancer phenotypes. Here, we evaluate loss of the TGF-β pathway signal …