Hypoxia drives CD39-dependent suppressor function in exhausted T cells to limit antitumor immunity

PDA Vignali, K DePeaux, MLJ Watson, C Ye… - Nature …, 2023 - nature.com
CD8+ T cells are critical for elimination of cancer cells. Factors within the tumor
microenvironment (TME) can drive these cells to a hypofunctional state known as …
被引用次数：107 相关文章
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[HTML][HTML] Tumor hypoxia drives CD39-dependent suppressor function in exhausted T cells limiting anti-tumor immunity

PDA Vignali, KD DePeaux, MJ Watson, C Ye… - Nature …, 2023 - ncbi.nlm.nih.gov
While CD8+ T cells are critical for elimination of cancer cells, factors within the tumor
microenvironment (TME) drive them to a hypofunctional state: exhaustion. The most …

Hypoxia drives CD39-dependent suppressor function in exhausted T cells to limit antitumor immunity.

PDA Vignali, K DePeaux, MJ Watson, C Ye… - Nature …, 2022 - europepmc.org
CD8+ T cells are critical for elimination of cancer cells. Factors within the tumor
microenvironment (TME) can drive these cells to a hypofunctional state known as …

Hypoxia drives CD39-dependent suppressor function in exhausted T cells to limit antitumor immunity

PDA Vignali, K DePeaux, MLJ Watson… - Nature …, 2023 - pubmed.ncbi.nlm.nih.gov
CD8+ T cells are critical for elimination of cancer cells. Factors within the tumor
microenvironment (TME) can drive these cells to a hypofunctional state known as …

Hypoxia drives CD39-dependent suppressor function in exhausted T cells to limit antitumor immunity

PDA Vignali, K DePeaux, MLJ Watson, C Ye, BR Ford… - paper.sciencenet.cn
CD8+ T cells are critical for elimination of cancer cells. Factors within the tumor
microenvironment (TME) can drive these cells to a hypofunctional state known as …

[引用][C] Tumor hypoxia drives CD39-dependent suppressor function in exhausted T cells limiting anti-tumor immunity

PDA Vignali, KD DePeaux, MJ Watson, C Ye… - Nat Immunol, 2023 - europepmc.org
While CD8+ T cells are critical for elimination of cancer cells, factors within the tumor
microenvironment (TME) drive them to a hypofunctional state: exhaustion. The most …