Synthetic cytokine circuits that drive T cells into immune-excluded tumors
Chimeric antigen receptor (CAR) T cells are ineffective against solid tumors with
immunosuppressive microenvironments. To overcome suppression, we engineered circuits …
immunosuppressive microenvironments. To overcome suppression, we engineered circuits …
Synthetic cytokine circuits that drive T cells into immune-excluded tumors.
GM Allen, NW Frankel, NR Reddy… - Science (New York …, 2022 - europepmc.org
CAR T cells are ineffective against solid tumors with immunosuppressive
microenvironments. To overcome suppression, we engineered circuits in which tumor …
microenvironments. To overcome suppression, we engineered circuits in which tumor …
[PDF][PDF] Synthetic cytokine circuits that drive T cells into immune-excluded tumors
GM Allen, NW Frankel, NR Reddy, HK Bhargava… - limlab.ucsf.edu
RESULTS: We observed that engineered synNotch→ IL-2 induction circuits drove potent
infiltration of chimeric antigen receptor (CAR) or TCR T cells into immune-excluded tumor …
infiltration of chimeric antigen receptor (CAR) or TCR T cells into immune-excluded tumor …
Synthetic cytokine circuits that drive T cells into immune-excluded tumors
GM Allen, NW Frankel, NR Reddy… - … (New York, NY), 2022 - pubmed.ncbi.nlm.nih.gov
Chimeric antigen receptor (CAR) T cells are ineffective against solid tumors with
immunosuppressive microenvironments. To overcome suppression, we engineered circuits …
immunosuppressive microenvironments. To overcome suppression, we engineered circuits …
[PDF][PDF] Synthetic cytokine circuits that drive T cells into immune-excluded tumors
GM Allen, NW Frankel, NR Reddy, HK Bhargava… - hershbhargava.com
RESULTS: We observed that engineered synNotch→ IL-2 induction circuits drove potent
infiltration of chimeric antigen receptor (CAR) or TCR T cells into immune-excluded tumor …
infiltration of chimeric antigen receptor (CAR) or TCR T cells into immune-excluded tumor …
[PDF][PDF] Synthetic cytokine circuits that drive T cells into immune-excluded tumors
GM Allen, NW Frankel, NR Reddy, HK Bhargava… - marcherin.be
RESULTS: We observed that engineered synNotch→ IL-2 induction circuits drove potent
infiltration of chimeric antigen receptor (CAR) or TCR T cells into immune-excluded tumor …
infiltration of chimeric antigen receptor (CAR) or TCR T cells into immune-excluded tumor …
[HTML][HTML] Synthetic cytokine circuits that drive T cell infiltration into immune-excluded tumors
GM Allen, NW Frankel, NR Reddy… - Science (New York …, 2022 - ncbi.nlm.nih.gov
CAR T cells are ineffective against solid tumors with immunosuppressive
microenvironments. To overcome suppression, we engineered circuits in which tumor …
microenvironments. To overcome suppression, we engineered circuits in which tumor …
Synthetic cytokine circuits that drive T cells into immune-excluded tumors
GM Allen, NW Frankel, NR Reddy, HK Bhargava… - paper.sciencenet.cn
Chimeric antigen receptor (CAR) T cells are ineffective against solid tumors with
immunosuppressive microenvironments. To overcome suppression, we engineered circuits …
immunosuppressive microenvironments. To overcome suppression, we engineered circuits …
Synthetic cytokine circuits that drive T cells into immune-excluded tumors.
G Allen, N Frankel, N Reddy, H Bhargava, M Yoshida… - Science, 2022 - escholarship.org
Chimeric antigen receptor (CAR) T cells are ineffective against solid tumors with
immunosuppressive microenvironments. To overcome suppression, we engineered circuits …
immunosuppressive microenvironments. To overcome suppression, we engineered circuits …
Synthetic cytokine circuits that drive T cells into immune-excluded tumors.
GM Allen, NW Frankel, NR Reddy… - Science (New York …, 2022 - europepmc.org
Chimeric antigen receptor (CAR) T cells are ineffective against solid tumors with
immunosuppressive microenvironments. To overcome suppression, we engineered circuits …
immunosuppressive microenvironments. To overcome suppression, we engineered circuits …