Aberrant ATM signaling and homology-directed DNA repair as a vulnerability of p53-mutant GBM to AZD1390-mediated radiosensitization

J Chen, DJ Laverty, S Talele, A Bale… - Science translational …, 2024 - science.org
ATM is a key mediator of radiation response, and pharmacological inhibition of ATM is a
rational strategy to radiosensitize tumors. AZD1390 is a brain-penetrant ATM inhibitor and a …
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Aberrant ATM signaling and homology-directed DNA repair as a vulnerability of p53-mutant GBM to AZD1390-mediated radiosensitization

J Chen, DJ Laverty, SM Talele, A Bale… - Science Translational …, 2024 - experts.umn.edu
ATM is a key mediator of radiation response, and pharmacological inhibition of ATM is a
rational strategy to radiosensitize tumors. AZD1390 is a brain-penetrant ATM inhibitor and a …

Aberrant ATM signaling and homology-directed DNA repair as a vulnerability of p53-mutant GBM to AZD1390-mediated radiosensitization

J Chen, DJ Laverty, S Talele, A Bale… - Science …, 2024 - pubmed.ncbi.nlm.nih.gov
ATM is a key mediator of radiation response, and pharmacological inhibition of ATM is a
rational strategy to radiosensitize tumors. AZD1390 is a brain-penetrant ATM inhibitor and a …

Aberrant ATM signaling and homology-directed DNA repair as a vulnerability of p53-mutant GBM to AZD1390-mediated radiosensitization.

J Chen, DJ Laverty, S Talele, A Bale… - Science …, 2024 - search.ebscohost.com
ATM is a key mediator of radiation response, and pharmacological inhibition of ATM is a
rational strategy to radiosensitize tumors. AZD1390 is a brain-penetrant ATM inhibitor and a …

Aberrant ATM signaling and homology-directed DNA repair as a vulnerability of p53-mutant GBM to AZD1390-mediated radiosensitization

J Chen, DJ Laverty, S Talele, A Bale… - Science …, 2024 - experts.illinois.edu
ATM is a key mediator of radiation response, and pharmacological inhibition of ATM is a
rational strategy to radiosensitize tumors. AZD1390 is a brain-penetrant ATM inhibitor and a …

Aberrant ATM signaling and homology-directed DNA repair as a vulnerability of p53-mutant GBM to AZD1390-mediated radiosensitization.

J Chen, DJ Laverty, S Talele, A Bale… - Science Translational …, 2024 - europepmc.org
ATM is a key mediator of radiation response, and pharmacological inhibition of ATM is a
rational strategy to radiosensitize tumors. AZD1390 is a brain-penetrant ATM inhibitor and a …

Aberrant ATM signaling and homology-directed DNA repair as a vulnerability of p53-mutant GBM to AZD1390-mediated radiosensitization

J Chen, DJ Laverty, S Talele… - Science …, 2024 - mayoclinic.elsevierpure.com
ATM is a key mediator of radiation response, and pharmacological inhibition of ATM is a
rational strategy to radiosensitize tumors. AZD1390 is a brain-penetrant ATM inhibitor and a …