Tumor-initiating cells establish an IL-33–TGF-β niche signaling loop to promote cancer progression

S Taniguchi, A Elhance, A Van Duzer, S Kumar… - Science, 2020 - science.org
INTRODUCTION A small subset of tumor cells with long-term tumorigenic capacity, known
as tumor-initiating cells (TICs), play a pivotal role in cancer development and therapy …

Tumor-initiating cells establish an IL-33-TGF-β niche signaling loop to promote cancer progression.

S Taniguchi, A Elhance, A Van Duzer… - Science (New York …, 2020 - europepmc.org
RESULTS: Focusing on the cytokine milieu and immune cells in the proximity of TGF-β–
responding TICs, here, we address how TICs generate a spatially distinct niche …

Tumor-initiating cells establish an IL-33–TGF-β niche signaling loop to promote cancer progression

S Taniguchi, A Elhance, A Van Duzer, S Kumar… - paper.sciencenet.cn
Targeting the cross-talk between tumor-initiating cells (TICs) and the niche
microenvironment is an attractive avenue for cancer therapy. We show here, using a mouse …

Tumor-initiating cells establish an IL-33–TGF-β niche signaling loop to promote cancer progression

S Taniguchi, A Elhance, A Van Duzer, S Kumar… - Science, 2020 - cir.nii.ac.jp
抄録< jats: title> Deconstructing a perilous loop</jats: title>< jats: p> Cancer cells that give
rise to solid tumors reside in a specialized microenvironment containing growth factors that …

Tumor-initiating cells establish an IL-33–TGF-b niche signaling loop to promote cancer progression

S Taniguchi, A Elhance, A van Duzer, S Kumar… - Science, 2020 - ohsu.elsevierpure.com
Targeting the cross-talk between tumor-initiating cells (TICs) and the niche
microenvironment is an attractive avenue for cancer therapy. We show here, using a mouse …

[HTML][HTML] Tumor-initiating cells establish an IL-33-TGF-β niche signaling loop to promote cancer progression

S Taniguchi, A Elhance, A Van Duzer… - Science (New York …, 2020 - ncbi.nlm.nih.gov
RESULTS: Focusing on the cytokine milieu and immune cells in the proximity of TGF-β–
responding TICs, here, we address how TICs generate a spatially distinct niche …

Tumor-initiating cells establish an IL-33-TGF-β niche signaling loop to promote cancer progression

S Taniguchi, A Elhance, A Van Duzer… - … (New York, NY), 2020 - pubmed.ncbi.nlm.nih.gov
Targeting the cross-talk between tumor-initiating cells (TICs) and the niche
microenvironment is an attractive avenue for cancer therapy. We show here, using a mouse …

Tumor-initiating cells establish an IL-33-TGF-β niche signaling loop to promote cancer progression.

S Taniguchi, A Elhance, A Van Duzer… - Science (New York …, 2020 - europepmc.org
Tumor-initiating cells establish an IL-33-TGF-β niche signaling loop to promote cancer
progression. - Abstract - Europe PMC Sign in | Create an account https://orcid.org Europe PMC …

Tumor-initiating cells establish an IL-33–TGF-β niche signaling loop to promote cancer progression

S Taniguchi, A Elhance, A Van Duzer, S Kumar… - paper.sciencenet.cn
Targeting the cross-talk between tumor-initiating cells (TICs) and the niche
microenvironment is an attractive avenue for cancer therapy. We show here, using a mouse …