[HTML][HTML] CFTR transmembrane segments are impaired in their conformational adaptability by a pathogenic loop mutation and dynamically stabilized by Lumacaftor

G Krainer, M Schenkel, A Hartmann… - Journal of Biological …, 2020 - ASBMB
The cystic fibrosis transmembrane conductance regulator (CFTR) is an ion channel protein
that is defective in individuals with cystic fibrosis (CF). To advance the rational design of CF …

CFTR transmembrane segments are impaired in their conformational adaptability by a pathogenic loop mutation and dynamically stabilized by Lumacaftor

G Krainer, M Schenkel, A Hartmann… - The Journal of …, 2020 - pubmed.ncbi.nlm.nih.gov
The cystic fibrosis transmembrane conductance regulator (CFTR) is an ion channel protein
that is defective in individuals with cystic fibrosis (CF). To advance the rational design of CF …

CFTR transmembrane segments are impaired in their conformational adaptability by a pathogenic loop mutation and dynamically stabilized by Lumacaftor.

G Krainer, M Schenkel, A Hartmann… - The Journal of …, 2019 - europepmc.org
The cystic fibrosis transmembrane conductance regulator (CFTR) is an ion channel protein
that is defective in individuals with cystic fibrosis (CF). To advance the rational design of CF …

[HTML][HTML] CFTR transmembrane segments are impaired in their conformational adaptability by a pathogenic loop mutation and dynamically stabilized by Lumacaftor

G Krainer, M Schenkel, A Hartmann… - Journal of Biological …, 2020 - Elsevier
The cystic fibrosis transmembrane conductance regulator (CFTR) is an ion channel protein
that is defective in individuals with cystic fibrosis (CF). To advance the rational design of CF …

[HTML][HTML] CFTR transmembrane segments are impaired in their conformational adaptability by a pathogenic loop mutation and dynamically stabilized by Lumacaftor

G Krainer, M Schenkel, A Hartmann… - The Journal of …, 2020 - ncbi.nlm.nih.gov
The cystic fibrosis transmembrane conductance regulator (CFTR) is an ion channel protein
that is defective in individuals with cystic fibrosis (CF). To advance the rational design of CF …