[HTML][HTML] Epigenetic priming by hypomethylation enhances the immunogenic potential of tolinapant in T-cell lymphoma

GA Ward, Z Zhang, S Jueliger, IS Potapov… - Cancer Research …, 2024 - AACR
Programmed cell death mechanisms are important for the regulation of tumor development
and progression. Evasion of and resistance to apoptosis are significant factors in …

Epigenetic Priming by Hypomethylation Enhances the Immunogenic Potential of Tolinapant in T-cell Lymphoma

GA Ward, Z Zhang, S Jueliger, IS Potapov… - Cancer Research …, 2024 - AACR
Programmed cell death mechanisms are important for the regulation of tumor development
and progression. Evasion of and resistance to apoptosis are significant factors in …

Epigenetic priming by hypomethylation enhances the immunogenic potential of tolinapant in T-cell lymphoma.

GA Ward, Z Zhang, S Jueliger, IS Potapov… - Cancer Research …, 2024 - europepmc.org
Programmed cell death mechanisms are important for the regulation of tumor development
and progression. Evasion of and resistance to apoptosis are significant factors in …

Epigenetic Priming by Hypomethylation Enhances the Immunogenic Potential of Tolinapant in T-cell Lymphoma

GA Ward, Z Zhang, S Jueliger… - Cancer research …, 2024 - pubmed.ncbi.nlm.nih.gov
Programmed cell death mechanisms are important for the regulation of tumor development
and progression. Evasion of and resistance to apoptosis are significant factors in …

[HTML][HTML] Epigenetic Priming by Hypomethylation Enhances the Immunogenic Potential of Tolinapant in T-cell Lymphoma

GA Ward, Z Zhang, S Jueliger, IS Potapov… - Cancer Research …, 2024 - ncbi.nlm.nih.gov
Programmed cell death mechanisms are important for the regulation of tumor development
and progression. Evasion of and resistance to apoptosis are significant factors in …

[PDF][PDF] Epigenetic priming by hypomethylation enhances the immunogenic potential of tolinapant in T-cell lymphoma

G Ward, Z Zhang, S Jueliger, MJ Sims, I Potapov… - astx.com
Tolinapant (ASTX660) is a potent, non-peptidomimetic antagonist of cIAP1, cIAP2 and XIAP
1, 2, and has demonstrated immunomodulatory properties in pre-clinical models of T-cell …