OLT1177, a β-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation
C Marchetti, B Swartzwelter… - Proceedings of the …, 2018 - National Acad Sciences
Activation of the NLRP3 inflammasome induces maturation of IL-1β and IL-18, both
validated targets for treating acute and chronic inflammatory diseases. Here, we …
validated targets for treating acute and chronic inflammatory diseases. Here, we …
[PDF][PDF] OLT1177, a beta-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation
C Marchetti, B Swartzwelter, F Gamboni, CP Neff… - 2018 - repository.ubn.ru.nl
Results OLT1177 Suppresses IL-1β and IL-18 Release with No Effect on Priming or TNFα.
The structure of OLT1177 is depicted in Fig. 1A and is verified as described in SI Appendix …
The structure of OLT1177 is depicted in Fig. 1A and is verified as described in SI Appendix …
OLT1177, a β-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation
C Marchetti, B Swartzwelter, F Gamboni, CP Neff… - Proceedings of the …, 2018 - JSTOR
Activation of the NLRP3 inflammasome induces maturation of IL-1β and IL-18, both
validated targets for treating acute and chronic inflammatory diseases. Here, we …
validated targets for treating acute and chronic inflammatory diseases. Here, we …
[PDF][PDF] OLT1177, a β-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation
C Marchettia, B Swartzweltera, F Gambonia, CP Neffa… - academia.edu
Results OLT1177 Suppresses IL-1β and IL-18 Release with No Effect on Priming or TNFα.
The structure of OLT1177 is depicted in Fig. 1A and is verified as described in SI Appendix …
The structure of OLT1177 is depicted in Fig. 1A and is verified as described in SI Appendix …
[PDF][PDF] OLT1177, a β-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation
C Marchettia, B Swartzweltera, F Gambonia, CP Neffa… - scienceopen.com
Results OLT1177 Suppresses IL-1β and IL-18 Release with No Effect on Priming or TNFα.
The structure of OLT1177 is depicted in Fig. 1A and is verified as described in SI Appendix …
The structure of OLT1177 is depicted in Fig. 1A and is verified as described in SI Appendix …
OLT1177, a β-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation
C Marchetti, B Swartzwelter… - Proceedings of the …, 2018 - pubmed.ncbi.nlm.nih.gov
Activation of the NLRP3 inflammasome induces maturation of IL-1β and IL-18, both
validated targets for treating acute and chronic inflammatory diseases. Here, we …
validated targets for treating acute and chronic inflammatory diseases. Here, we …
[HTML][HTML] OLT1177, a β-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation
C Marchetti, B Swartzwelter, F Gamboni… - Proceedings of the …, 2018 - ncbi.nlm.nih.gov
Results OLT1177 Suppresses IL-1β and IL-18 Release with No Effect on Priming or TNFα.
The structure of OLT1177 is depicted in Fig. 1A and is verified as described in SI Appendix …
The structure of OLT1177 is depicted in Fig. 1A and is verified as described in SI Appendix …
[PDF][PDF] OLT1177, a β-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation
C Marchettia, B Swartzweltera, F Gambonia, CP Neffa… - researchgate.net
Results OLT1177 Suppresses IL-1β and IL-18 Release with No Effect on Priming or TNFα.
The structure of OLT1177 is depicted in Fig. 1A and is verified as described in SI Appendix …
The structure of OLT1177 is depicted in Fig. 1A and is verified as described in SI Appendix …
OLT1177, a β-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation
C Marchetti, B Swartzwelter, F Gamboni… - Proceedings of the …, 2018 - cir.nii.ac.jp
抄録< jats: title> Significance</jats: title>< jats: p> The NLRP3 inflammasome is an
intracellular oligomer regulating the activation of caspase-1 for the processing and secretion …
intracellular oligomer regulating the activation of caspase-1 for the processing and secretion …
[PDF][PDF] OLT1177, a β-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation
C Marchettia, B Swartzweltera, F Gambonia, CP Neffa… - core.ac.uk
Results OLT1177 Suppresses IL-1β and IL-18 Release with No Effect on Priming or TNFα.
The structure of OLT1177 is depicted in Fig. 1A and is verified as described in SI Appendix …
The structure of OLT1177 is depicted in Fig. 1A and is verified as described in SI Appendix …