Dissolution challenges associated with the surface pH of drug particles: integration into mechanistic oral absorption modeling

B Hens, N Seegobin, M Bermejo, Y Tsume, N Clear… - The AAPS Journal, 2022 - Springer
The present work aimed to differentiate between in vitro dissolution profiles of ibuprofen as
input for GastroPlus™ and to see the impact on systemic exposure. In vitro dissolution …
被引用次数：14 相关文章

Dissolution Challenges Associated with the Surface pH of Drug Particles: Integration into Mechanistic Oral Absorption Modeling.

B Hens, N Seegobin, M Bermejo, Y Tsume… - The AAPS …, 2022 - europepmc.org
The present work aimed to differentiate between in vitro dissolution profiles of ibuprofen as
input for GastroPlus™ and to see the impact on systemic exposure. In vitro dissolution …

Dissolution Challenges Associated with the Surface pH of Drug Particles: Integration into Mechanistic Oral Absorption Modeling

B Hens, N Seegobin, M Bermejo… - The AAPS …, 2022 - pubmed.ncbi.nlm.nih.gov
The present work aimed to differentiate between in vitro dissolution profiles of ibuprofen as
input for GastroPlus™ and to see the impact on systemic exposure. In vitro dissolution …