Increased gene expression variability hinders the formation of regional mechanical conflicts leading to reduced organ shape robustness

DC Trinh, M Martin, L Bald, A Maizel… - Proceedings of the …, 2023 - National Acad Sciences
To relate gene networks and organ shape, one needs to address two wicked problems: i)
Gene expression is often variable locally, and shape is reproducible globally; ii) gene …

Increased gene expression variability hinders the formation of regional mechanical conflicts leading to reduced organ shape robustness

DC Trinh, M Martin, L Bald, A Maizel… - Proceedings of the …, 2023 - pubmed.ncbi.nlm.nih.gov
To relate gene networks and organ shape, one needs to address two wicked problems: i)
Gene expression is often variable locally, and shape is reproducible globally; ii) gene …

[HTML][HTML] Increased gene expression variability hinders the formation of regional mechanical conflicts leading to reduced organ shape robustness

DC Trinh, M Martin, L Bald, A Maizel… - Proceedings of the …, 2023 - ncbi.nlm.nih.gov
Results Mutation in VIP3 Increases the Variability in Linker Histone H1 Expression between
Sister Guard Cells. To see whether mutation in VIP3 could lead to increased gene …

Increased gene expression variability hinders the formation of regional mechanical conflicts leading to reduced organ shape robustness.

DC Trinh, M Martin, L Bald, A Maizel… - Proceedings of the …, 2023 - europepmc.org
Results Mutation in VIP3 Increases the Variability in Linker Histone H1 Expression between
Sister Guard Cells. To see whether mutation in VIP3 could lead to increased gene …

Increased gene expression variability hinders the formation of regional mechanical conflicts leading to reduced organ shape robustness

DC Trinh, M Martin, L Bald, A Maizel… - Proceedings of the …, 2023 - ui.adsabs.harvard.edu
There is more and more evidence that transcriptional noise exists in both unicellular and
multicellular systems, but the contribution of transcriptional noise to organ robustness is …

Increased gene expression variability hinders the formation of regional mechanical conflicts leading to reduced organ shape robustness.

DC Trinh, M Martin, L Bald, A Maizel… - Proceedings of the …, 2023 - europepmc.org
To relate gene networks and organ shape, one needs to address two wicked problems: i)
Gene expression is often variable locally, and shape is reproducible globally; ii) gene …