Emergence of compensatory mutations reveals the importance of electrostatic interactions between HIV-1 integrase and genomic RNA

C Shema Mugisha, T Dinh, A Kumar, K Tenneti… - MBio, 2022 - Am Soc Microbiol
ABSTRACT HIV-1 integrase (IN) has a noncatalytic function in virion maturation through its
binding to the viral RNA genome (gRNA). Class II IN substitutions inhibit IN-gRNA binding …

Emergence of compensatory mutations reveals the importance of electrostatic interactions between HIV-1 integrase and genomic RNA

C Shema Mugisha, T Dinh, A Kumar, K Tenneti… - 2022 - digitalcommons.wustl.edu
ABSTRACT HIV-1 integrase (IN) has a noncatalytic function in virion maturation through its
binding to the viral RNA genome (gRNA). Class II IN substitutions inhibit IN-gRNA binding …

Emergence of Compensatory Mutations Reveals the Importance of Electrostatic Interactions between HIV-1 Integrase and Genomic RNA

CS Mugisha, T Dinh, A Kumar, K Tenneti, JE Eschbach… - mBio, 2022 - profiles.wustl.edu
Abstract HIV-1 integrase (IN) has a noncatalytic function in virion maturation through its
binding to the viral RNA genome (gRNA). Class II IN substitutions inhibit IN-gRNA binding …

[HTML][HTML] Emergence of Compensatory Mutations Reveals the Importance of Electrostatic Interactions between HIV-1 Integrase and Genomic RNA

CS Mugisha, T Dinh, A Kumar, K Tenneti, JE Eschbach… - mBio, 2022 - ncbi.nlm.nih.gov
ABSTRACT HIV-1 integrase (IN) has a noncatalytic function in virion maturation through its
binding to the viral RNA genome (gRNA). Class II IN substitutions inhibit IN-gRNA binding …

[PDF][PDF] Emergence of Compensatory Mutations Reveals the Importance of Electrostatic Interactions between HIV-1 Integrase and Genomic RNA

CS Mugisha, T Dinh, A Kumar, K Tenneti, JE Eschbach… - 2022 - researchgate.net
ABSTRACT HIV-1 integrase (IN) has a noncatalytic function in virion maturation through its
binding to the viral RNA genome (gRNA). Class II IN substitutions inhibit IN-gRNA binding …

Emergence of Compensatory Mutations Reveals the Importance of Electrostatic Interactions between HIV-1 Integrase and Genomic RNA

CS Mugisha, T Dinh, A Kumar, K Tenneti, JE Eschbach… - 2022 - agris.fao.org
ABSTRACT HIV-1 integrase (IN) has a noncatalytic function in virion maturation through its
binding to the viral RNA genome (gRNA). Class II IN substitutions inhibit IN-gRNA binding …

Emergence of Compensatory Mutations Reveals the Importance of Electrostatic Interactions between HIV-1 Integrase and Genomic RNA.

T Dinh, A Kumar, K Tenneti, JE Eschbach, K Davis… - Mbio, 2022 - europepmc.org
ABSTRACT HIV-1 integrase (IN) has a noncatalytic function in virion maturation through its
binding to the viral RNA genome (gRNA). Class II IN substitutions inhibit IN-gRNA binding …

Emergence of compensatory mutations reveal the importance of electrostatic interactions between HIV-1 integrase and genomic RNA

CS Mugisha, T Dinh, K Tenneti, JE Eschbach, K Davis… - bioRxiv, 2021 - biorxiv.org
Independent of its catalytic activity, HIV-1 integrase (IN) enzyme regulates proper particle
maturation by binding to and packaging the viral RNA genome (gRNA) inside the mature …

Emergence of Compensatory Mutations Reveals the Importance of Electrostatic Interactions between HIV-1 Integrase and Genomic RNA

CS Mugisha, T Dinh, A Kumar, K Tenneti, JE Eschbach… - mBio, 2022 - Elsevier
ABSTRACT HIV-1 integrase (IN) has a noncatalytic function in virion maturation through its
binding to the viral RNA genome (gRNA). Class II IN substitutions inhibit IN-gRNA binding …

Emergence of compensatory mutations reveals the importance of electrostatic interactions between HIV-1 integrase and genomic RNA

C Shema Mugisha, T Dinh, A Kumar, K Tenneti… - mBio, 2022 - eprints.gla.ac.uk
HIV-1 integrase (IN) has a noncatalytic function in virion maturation through its binding to the
viral RNA genome (gRNA). Class II IN substitutions inhibit IN-gRNA binding and result in the …