Low protease activity in B cell follicles promotes retention of intact antigens after immunization

A Aung, A Cui, L Maiorino, AP Amini, JR Gregory… - Science, 2023 - science.org
The structural integrity of vaccine antigens is critical to the generation of protective antibody
responses, but the impact of protease activity on vaccination in vivo is poorly understood …
被引用次数：40 相关文章
[HTML] nih.gov

[HTML][HTML] Low protease activity in B cell follicles promotes retention of intact antigens after immunization

A Aung, A Cui, L Maiorino, AP Amini… - Science (New York …, 2023 - ncbi.nlm.nih.gov
The structural integrity of vaccine antigens is critical to the generation of protective antibody
responses, but the impact of protease activity on vaccination in vivo is poorly understood …

Low protease activity in B cell follicles promotes retention of intact antigens after immunization

A Aung, A Cui, L Maiorino, AP Amini, JR Gregory… - paper.sciencenet.cn
The structural integrity of vaccine antigens is critical to the generation of protective antibody
responses, but the impact of protease activity on vaccination in vivo is poorly understood …

Low protease activity in B cell follicles promotes retention of intact antigens after immunization

A Aung, A Cui, L Maiorino, AP Amini… - … (New York, NY), 2023 - pubmed.ncbi.nlm.nih.gov
The structural integrity of vaccine antigens is critical to the generation of protective antibody
responses, but the impact of protease activity on vaccination in vivo is poorly understood …

Low protease activity in B cell follicles promotes retention of intact antigens after immunization.

A Aung, A Cui, L Maiorino, AP Amini… - Science (New York …, 2023 - europepmc.org
The structural integrity of vaccine antigens is critical to the generation of protective antibody
responses, but the impact of protease activity on vaccination in vivo is poorly understood …
[PDF] mit.edu

[PDF][PDF] Low protease activity in B cell follicles promotes retention of intact antigens after immunization

A Aung, A Cui, L Maiorino, AP Amini, JR Gregory… - gen - lmrt.mit.edu
RESULTS: We investigated antigen stability within the LN by conjugating antigens with dyes
that undergo a loss in fluorescence resonance energy transfer (FRET) upon structural …

[引用][C] Low protease activity in B cell follicles promotes retention of intact antigens after immunization

A Aung, A Cui, L Maiorino, AP Amini, JR Gregory… - Science, 2023 - europepmc.org
The structural integrity of vaccine antigens is critical to the generation of protective antibody
responses, but the impact of protease activity on vaccination in vivo is poorly understood …