Human carboxylesterase 1A plays a predominant role in the hydrolytic activation of remdesivir in humans

F Zhang, HX Li, TT Zhang, Y Xiong, HN Wang… - Chemico-Biological …, 2022 - Elsevier
Remdesivir, an intravenous nucleotide prodrug, has been approved for treating COVID-19 in
hospitalized adults and pediatric patients. Upon administration, remdesivir can be readily …

Human carboxylesterase 1A plays a predominant role in the hydrolytic activation of remdesivir in humans.

F Zhang, HX Li, TT Zhang, Y Xiong… - Chemico-biological …, 2021 - europepmc.org
Remdesivir, an intravenous nucleotide prodrug, has been approved for treating COVID-19 in
hospitalized adults and pediatric patients. Upon administration, remdesivir can be readily …

Human carboxylesterase 1A plays a predominant role in the hydrolytic activation of remdesivir in humans

F Zhang, HX Li, TT Zhang, Y Xiong… - Chemico …, 2022 - pubmed.ncbi.nlm.nih.gov
Remdesivir, an intravenous nucleotide prodrug, has been approved for treating COVID-19 in
hospitalized adults and pediatric patients. Upon administration, remdesivir can be readily …

Human carboxylesterase 1A plays a predominant role in the hydrolytic activation of remdesivir in humans

F Zhang, HX Li, TT Zhang, Y Xiong… - Chemico-Biological …, 2022 - ui.adsabs.harvard.edu
Remdesivir, an intravenous nucleotide prodrug, has been approved for treating COVID-19 in
hospitalized adults and pediatric patients. Upon administration, remdesivir can be readily …