MTH1 inhibitor TH588 disturbs mitotic progression and induces mitosis-dependent accumulation of genomic 8-oxodG

SG Rudd, H Gad, K Sanjiv, N Amaral, A Hagenkort… - Cancer Research, 2020 - AACR
Reactive oxygen species (ROS) oxidize nucleotide triphosphate pools (eg, 8-oxodGTP),
which may kill cells if incorporated into DNA. Whether cancers avoid poisoning from …

MTH1 Inhibitor TH588 Disturbs Mitotic Progression and Induces Mitosis-Dependent Accumulation of Genomic 8-oxodG

SG Rudd, H Gad, K Sanjiv, N Amaral… - Cancer …, 2020 - pubmed.ncbi.nlm.nih.gov
Reactive oxygen species (ROS) oxidize nucleotide triphosphate pools (eg, 8-oxodGTP),
which may kill cells if incorporated into DNA. Whether cancers avoid poisoning from …

MTH1 Inhibitor TH588 Disturbs Mitotic Progression and Induces Mitosis-Dependent Accumulation of Genomic 8-oxodG.

SG Rudd, H Gad, K Sanjiv, N Amaral… - Cancer …, 2020 - europepmc.org
Reactive oxygen species (ROS) oxidize nucleotide triphosphate pools (eg, 8-oxodGTP),
which may kill cells if incorporated into DNA. Whether cancers avoid poisoning from …

MTH1 inhibitor TH588 disturbs mitotic progression and induces mitosis-dependent accumulation of genomic 8-oxodG

SG Rudd, H Gad, K Sanjiv, N Amaral… - Cancer …, 2020 - eprints.whiterose.ac.uk
Reactive oxygen species (ROS) oxidize nucleotide triphosphate pools (eg, 8-oxodGTP),
which may kill cells if incorporated into DNA. Whether cancers avoid poisoning from …