Model-based optimization of cooling crystallization of active pharmaceutical ingredients undergoing thermal degradation

K Pal, Y Yang, ZK Nagy - Crystal Growth & Design, 2019 - ACS Publications
Many active pharmaceutical ingredients (APIs) undergo degradation at high temperature.
Optimum cooling profiles from first principle models usually do not consider this degradation …
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[引用][C] Model Based Optimization of Cooling Crystallization of Active Pharmaceutical Ingredients Undergoing Thermal Degradation

K Pal, Z Nagy - 2019 AIChE Annual Meeting, 2019 - aiche.confex.com