Accurate classification of BRCA1 variants with saturation genome editing
GM Findlay, RM Daza, B Martin, MD Zhang, AP Leith… - Nature, 2018 - nature.com
Variants of uncertain significance fundamentally limit the clinical utility of genetic information.
The challenge they pose is epitomized by BRCA1, a tumour suppressor gene in which …
The challenge they pose is epitomized by BRCA1, a tumour suppressor gene in which …
Accurate classification of BRCA1 variants with saturation genome editing.
GM Findlay, RM Daza, B Martin, MD Zhang, AP Leith… - Nature, 2018 - europepmc.org
Variants of uncertain significance (VUS) fundamentally limit the clinical utility of genetic
information. The challenge they pose is epitomized by BRCA1, a tumor suppressor in which …
information. The challenge they pose is epitomized by BRCA1, a tumor suppressor in which …
Accurate classification of BRCA1 variants with saturation genome editing
GM Findlay, RM Daza, B Martin, MD Zhang… - …, 2018 - ui.adsabs.harvard.edu
Variants of uncertain significance fundamentally limit the clinical utility of genetic information.
The challenge they pose is epitomized by BRCA1, a tumour suppressor gene in which …
The challenge they pose is epitomized by BRCA1, a tumour suppressor gene in which …
Accurate classification of BRCA1 variants with saturation genome editing
GM Findlay, RM Daza, B Martin, MD Zhang… - …, 2018 - pubmed.ncbi.nlm.nih.gov
Variants of uncertain significance fundamentally limit the clinical utility of genetic information.
The challenge they pose is epitomized by BRCA1, a tumour suppressor gene in which …
The challenge they pose is epitomized by BRCA1, a tumour suppressor gene in which …
Accurate classification of BRCA1 variants with saturation genome editing
GM Findlay, RM Daza, B Martin, MD Zhang, AP Leith… - Nature, 2018 - go.gale.com
Variants of uncertain significance fundamentally limit the clinical utility of genetic information.
The challenge they pose is epitomized by BRCA1, a tumour suppressor gene in which …
The challenge they pose is epitomized by BRCA1, a tumour suppressor gene in which …
Accurate functional classification of thousands of BRCA1 variants with saturation genome editing
GM Findlay, RM Daza, B Martin, MD Zhang, AP Leith… - bioRxiv, 2018 - biorxiv.org
Variants of uncertain significance (VUS) fundamentally limit the utility of genetic information
in a clinical setting. The challenge of VUS is epitomized by BRCA1, a tumor suppressor …
in a clinical setting. The challenge of VUS is epitomized by BRCA1, a tumor suppressor …
Accurate classification of BRCA1 variants with saturation genome editing
GM Findlay, RM Daza, B Martin, MD Zhang, AP Leith… - Nature, 2018 - econpapers.repec.org
Variants of uncertain significance fundamentally limit the clinical utility of genetic information.
The challenge they pose is epitomized by BRCA1, a tumour suppressor gene in which …
The challenge they pose is epitomized by BRCA1, a tumour suppressor gene in which …
[HTML][HTML] Accurate classification of BRCA1 variants with saturation genome editing
GM Findlay, RM Daza, B Martin, MD Zhang, AP Leith… - Nature, 2018 - ncbi.nlm.nih.gov
Variants of uncertain significance (VUS) fundamentally limit the clinical utility of genetic
information. The challenge they pose is epitomized by BRCA1, a tumor suppressor in which …
information. The challenge they pose is epitomized by BRCA1, a tumor suppressor in which …
Accurate classification of BRCA1 variants with saturation genome editing
GM Findlay, RM Daza, B Martin, MD Zhang, AP Leith… - Nature, 2018 - ideas.repec.org
Variants of uncertain significance fundamentally limit the clinical utility of genetic information.
The challenge they pose is epitomized by BRCA1, a tumour suppressor gene in which …
The challenge they pose is epitomized by BRCA1, a tumour suppressor gene in which …
[PDF][PDF] Accurate classification of BR CAlvariants with saturation genome editing
GM Findlayl, RM Dazal, B Martinl, MD Zhangl, AP Leithl… - fstp-expert-system.typepad.com
Our ability to predict the phenotypic consequences of an arbitrary genetic variant in a human
genome remains poor. This problem is evidenced by the large numbers ofvariants …
genome remains poor. This problem is evidenced by the large numbers ofvariants …