Selective orexin 1 receptor antagonist SB-334867 aggravated cognitive dysfunction in 3xTg-AD mice

WR Gao, XH Hu, KY Yu, HY Cai, ZJ Wang… - Behavioural Brain …, 2023 - Elsevier
Cognitive dysfunction is the main clinical manifestation of Alzheimer's disease (AD).
Previous research found that elevated orexin level in the cerebrospinal fluid was closely …
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Selective orexin 1 receptor antagonist SB-334867 aggravated cognitive dysfunction in 3xTg-AD mice

WR Gao, XH Hu, KY Yu, HY Cai… - Behavioural brain …, 2023 - pubmed.ncbi.nlm.nih.gov
Cognitive dysfunction is the main clinical manifestation of Alzheimer's disease (AD).
Previous research found that elevated orexin level in the cerebrospinal fluid was closely …