[HTML][HTML] Exploring the chemical space of orally bioavailable PROTACs

G Apprato, V Poongavanam, DG Jimenez, Y Atilaw… - Drug Discovery …, 2024 - Elsevier
A principal challenge in the discovery of proteolysis targeting chimeras (PROTACs) as oral
medications is their bioavailability. To facilitate drug design, it is therefore essential to …

Exploring the chemical space of orally bioavailable PROTACs

G Apprato, V Poongavanam, DG Jimenez… - Drug discovery … - pubmed.ncbi.nlm.nih.gov
A principal challenge in the discovery of proteolysis targeting chimeras (PROTACs) as oral
medications is their bioavailability. To facilitate drug design, it is therefore essential to …

Exploring the chemical space of orally bioavailable PROTACs.

G Apprato, V Poongavanam, Y Atilaw… - Drug Discovery …, 2024 - europepmc.org
A principal challenge in the discovery of proteolysis targeting chimeras (PROTACs) as oral
medications is their bioavailability. To facilitate drug design, it is therefore essential to …