Liabilities associated with the formation of “hard” electrophiles in reactive metabolite trapping screens

AS Kalgutkar - Chemical research in toxicology, 2017 - ACS Publications
Soft electrophiles (eg, epoxides, quinones, quinone-imines, quinone-methides, etc.)
generated via the oxidative bioactivation of phenyl, phenolic, amino-, and alkylphenolic …

Liabilities Associated with the Formation of" Hard" Electrophiles in Reactive Metabolite Trapping Screens

AS Kalgutkar - Chemical research in toxicology, 2017 - pubmed.ncbi.nlm.nih.gov
Soft electrophiles (eg, epoxides, quinones, quinone-imines, quinone-methides, etc.)
generated via the oxidative bioactivation of phenyl, phenolic, amino-, and alkylphenolic …

Liabilities Associated with the Formation of" Hard" Electrophiles in Reactive Metabolite Trapping Screens.

AS Kalgutkar - Chemical Research in Toxicology, 2016 - europepmc.org
Soft electrophiles (eg, epoxides, quinones, quinone-imines, quinone-methides, etc.)
generated via the oxidative bioactivation of phenyl, phenolic, amino-, and alkylphenolic …