Demethylzeylasteral targets lactate by inhibiting histone lactylation to suppress the tumorigenicity of liver cancer stem cells

L Pan, F Feng, J Wu, S Fan, J Han, S Wang… - Pharmacological …, 2022 - Elsevier
Cancer stem cells drive tumor initiation, progression, and recurrence, which compromise the
effectiveness of anti-tumor drugs. Here, we report that demethylzeylasteral (DML), a …

Demethylzeylasteral targets lactate by inhibiting histone lactylation to suppress the tumorigenicity of liver cancer stem cells

L Pan, F Feng, J Wu, S Fan, J Han… - Pharmacological …, 2022 - pubmed.ncbi.nlm.nih.gov
Cancer stem cells drive tumor initiation, progression, and recurrence, which compromise the
effectiveness of anti-tumor drugs. Here, we report that demethylzeylasteral (DML), a …

Demethylzeylasteral targets lactate by inhibiting histone lactylation to suppress the tumorigenicity of liver cancer stem cells.

L Pan, F Feng, J Wu, S Fan, J Han, S Wang… - Pharmacological …, 2022 - europepmc.org
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lactate to suppress the tumorigenicity of liver cancer stem cells: Is it attributed to histone …