[HTML][HTML] Integrating distribution kinetics and toxicodynamics to assess repeat dose neurotoxicity in vitro using human BrainSpheres: a case study on amiodarone

C Nunes, S Proença, G Ambrosini, D Pamies… - Frontiers in …, 2023 - frontiersin.org
For ethical, economical, and scientific reasons, animal experimentation, used to evaluate the
potential neurotoxicity of chemicals before their release in the market, needs to be replaced …

[PDF][PDF] Integrating distribution kinetics and toxicodynamics to assess repeat dose neurotoxicity in vitro using human BrainSpheres: a case study on amiodarone

C Nunes, S Proença, G Ambrosini, D Pamies… - 2023 - core.ac.uk
The brain is structurally and functionally very complex. It is particularly susceptible to toxic
insults due to its very low regeneration abilities after damage. In spite of this vulnerability …

Integrating distribution kinetics and toxicodynamics to assess repeat dose neurotoxicity in vitro using human BrainSpheres: a case study on amiodarone

C Nunes, S Proença, G Ambrosini… - Frontiers in …, 2023 - europepmc.org
For ethical, economical, and scientific reasons, animal experimentation, used to evaluate the
potential neurotoxicity of chemicals before their release in the market, needs to be replaced …

[PDF][PDF] Integrating distribution kinetics and toxicodynamics to assess repeat dose neurotoxicity in vitro using human BrainSpheres: a case study on amiodarone

C Nunes, S Proença, G Ambrosini, D Pamies… - 2023 - edepot.wur.nl
The brain is structurally and functionally very complex. It is particularly susceptible to toxic
insults due to its very low regeneration abilities after damage. In spite of this vulnerability …

Integrating distribution kinetics and toxicodynamics to assess repeat dose neurotoxicity in vitro using human BrainSpheres: a case study on amiodarone

C Nunes, S Proença, G Ambrosini… - Frontiers in …, 2023 - research-collection.ethz.ch
For ethical, economical, and scientific reasons, animal experimentation, used to evaluate the
potential neurotoxicity of chemicals before their release in the market, needs to be replaced …

[HTML][HTML] Integrating distribution kinetics and toxicodynamics to assess repeat dose neurotoxicity in vitro using human BrainSpheres: a case study on amiodarone

C Nunes, S Proença, G Ambrosini… - Frontiers in …, 2023 - ncbi.nlm.nih.gov
For ethical, economical, and scientific reasons, animal experimentation, used to evaluate the
potential neurotoxicity of chemicals before their release in the market, needs to be replaced …

[PDF][PDF] Integrating distribution kinetics and toxicodynamics to assess repeat dose neurotoxicity in vitro using human BrainSpheres: a case study on amiodarone

C Nunes, S Proença, G Ambrosini, D Pamies… - 2023 - serval.unil.ch
The brain is structurally and functionally very complex. It is particularly susceptible to toxic
insults due to its very low regeneration abilities after damage. In spite of this vulnerability …

Integrating distribution kinetics and toxicodynamics to assess repeat dose neurotoxicity in vitro using human BrainSpheres: a case study on amiodarone

C Nunes, S Proença, G Ambrosini, D Pamies… - Frontiers in …, 2023 - library.wur.nl
For ethical, economical, and scientific reasons, animal experimentation, used to evaluate the
potential neurotoxicity of chemicals before their release in the market, needs to be replaced …

Integrating distribution kinetics and toxicodynamics to assess repeat dose neurotoxicity in vitro using human BrainSpheres: a case study on amiodarone

C Nunes, S Proença, G Ambrosini… - Frontiers in …, 2023 - pubmed.ncbi.nlm.nih.gov
For ethical, economical, and scientific reasons, animal experimentation, used to evaluate the
potential neurotoxicity of chemicals before their release in the market, needs to be replaced …

[PDF][PDF] Integrating distribution kinetics and toxicodynamics to assess repeat dose neurotoxicity in vitro using human BrainSpheres: a case study on amiodarone

C Nunes, S Proença, G Ambrosini, D Pamies… - 2023 - pdfs.semanticscholar.org
The brain is structurally and functionally very complex. It is particularly susceptible to toxic
insults due to its very low regeneration abilities after damage. In spite of this vulnerability …