Discovery of a potent and selective tyrosine kinase 2 inhibitor: TAK-279

S Leit, J Greenwood, S Carriero, S Mondal… - Journal of Medicinal …, 2023 - ACS Publications
TYK2 is a key mediator of IL12, IL23, and type I interferon signaling, and these cytokines
have been implicated in the pathogenesis of multiple inflammatory and autoimmune …
被引用次数：12 相关文章

Discovery of a Potent and Selective Tyrosine Kinase 2 Inhibitor: TAK-279.

S Leit, J Greenwood, S Carriero, S Mondal… - Journal of Medicinal …, 2023 - europepmc.org
TYK2 is a key mediator of IL12, IL23, and type I interferon signaling, and these cytokines
have been implicated in the pathogenesis of multiple inflammatory and autoimmune …

Discovery of a Potent and Selective Tyrosine Kinase 2 Inhibitor: TAK-279

S Leit, J Greenwood, S Carriero… - Journal of …, 2023 - pubmed.ncbi.nlm.nih.gov
TYK2 is a key mediator of IL12, IL23, and type I interferon signaling, and these cytokines
have been implicated in the pathogenesis of multiple inflammatory and autoimmune …