Hydroxycholesterol substitution in ionizable lipid nanoparticles for mRNA delivery to T cells

SK Patel, MM Billingsley, C Frazee, X Han… - Journal of Controlled …, 2022 - Elsevier
Delivery of nucleic acids, such as mRNA, to immune cells has become a major focus in the
past decade with ionizable lipid nanoparticles (LNPs) emerging as a clinically-validated …

[PDF][PDF] Hydroxycholesterol substitution in ionizable lipid nanoparticles for mRNA delivery to T cells

SK Patel, MM Billingsley, C Frazee… - Journal of …, 2022 - mitchell-lab.seas.upenn.edu
Delivery of nucleic acids, such as mRNA, to immune cells has become a major focus in the
past decade with ionizable lipid nanoparticles (LNPs) emerging as a clinically-validated …

Hydroxycholesterol Substitution in Ionizable Lipid Nanoparticles for mRNA Delivery to T Cells

SK Patel, MM Billingsley, C Frazee, X Han, K Swingle… - abstracts.biomaterials.org
Materials and Methods: A library of 24 LNPs was formulated using 6 X-hydroxycholesterol
modifications (7𝛼, 7𝛽, 19, 20, 24, 25). Each of the 6 hydroxycholesterols were substituted in …

[HTML][HTML] Hydroxycholesterol substitution in ionizable lipid nanoparticles for mRNA delivery to T cells

SK Patel, MM Billingsley, C Frazee, X Han… - Journal of controlled …, 2022 - ncbi.nlm.nih.gov
Delivery of nucleic acids, such as mRNA, to immune cells has become a major focus in the
past decade with ionizable lipid nanoparticles (LNPs) emerging as a clinically-validated …

Hydroxycholesterol substitution in ionizable lipid nanoparticles for mRNA delivery to T cells

SK Patel, MM Billingsley, C Frazee… - … : official journal of …, 2022 - pubmed.ncbi.nlm.nih.gov
Delivery of nucleic acids, such as mRNA, to immune cells has become a major focus in the
past decade with ionizable lipid nanoparticles (LNPs) emerging as a clinically-validated …

[PDF][PDF] Hydroxycholesterol substitution in ionizable lipid nanoparticles for mRNA delivery to T cells

SK Patel, MM Billingsley, C Frazee, X Han… - Journal of Controlled …, 2022 - par.nsf.gov
Delivery of nucleic acids, such as mRNA, to immune cells has become a major focus in the
past decade with ionizable lipid nanoparticles (LNPs) emerging as a clinically-validated …

Hydroxycholesterol substitution in ionizable lipid nanoparticles for mRNA delivery to T cells.

SK Patel, MM Billingsley, C Frazee, X Han… - Journal of Controlled …, 2022 - europepmc.org
Delivery of nucleic acids, such as mRNA, to immune cells has become a major focus in the
past decade with ionizable lipid nanoparticles (LNPs) emerging as a clinically-validated …

[引用][C] Hydroxycholesterol substitution in ionizable lipid nanoparticles for mRNA delivery to T cells

SK Patel, MM Billingsley, C Frazee, X Han, KL Swingle… - 2022