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[HTML][HTML] Investigating the relevance of CYP2J2 inhibition for drugs known to cause intermediate to high risk torsades de pointes

JWH Leow, Y Gu, ECY Chan - European Journal of Pharmaceutical …, 2023 - Elsevier
Abstract Cardiac cytochrome P450 2J2 (CYP2J2) metabolizes endogenous polyunsaturated
fatty acid, arachidonic acid (AA), to bioactive regioisomeric epoxyeicosatrienoic acid (EET) …
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Investigating the relevance of CYP2J2 inhibition for drugs known to cause intermediate to high risk torsades de pointes

JWH Leow, Y Gu, ECY Chan - European journal of …, 2023 - pubmed.ncbi.nlm.nih.gov
Cardiac cytochrome P450 2J2 (CYP2J2) metabolizes endogenous polyunsaturated fatty
acid, arachidonic acid (AA), to bioactive regioisomeric epoxyeicosatrienoic acid (EET) …

Investigating the relevance of CYP2J2 inhibition for drugs known to cause intermediate to high risk torsades de pointes.

JWH Leow, Y Gu, ECY Chan - European Journal of Pharmaceutical …, 2023 - europepmc.org
Cardiac cytochrome P450 2J2 (CYP2J2) metabolizes endogenous polyunsaturated fatty
acid, arachidonic acid (AA), to bioactive regioisomeric epoxyeicosatrienoic acid (EET) …