A highly efficient transgene knock-in technology in clinically relevant cell types

AG Allen, SQ Khan, CM Margulies… - Nature …, 2024 - nature.com
Inefficient knock-in of transgene cargos limits the potential of cell-based medicines. In this
study, we used a CRISPR nuclease that targets a site within an exon of an essential gene …
被引用次数：23 相关文章

A highly efficient transgene knock-in technology in clinically relevant cell types

AG Allen, SQ Khan, CM Margulies… - Nature …, 2024 - pubmed.ncbi.nlm.nih.gov
Inefficient knock-in of transgene cargos limits the potential of cell-based medicines. In this
study, we used a CRISPR nuclease that targets a site within an exon of an essential gene …

A highly efficient transgene knock-in technology in clinically relevant cell types.

AG Allen, SQ Khan, CM Margulies… - Nature …, 2023 - europepmc.org
Inefficient knock-in of transgene cargos limits the potential of cell-based medicines. In this
study, we used a CRISPR nuclease that targets a site within an exon of an essential gene …