Computational drug discovery for castration-resistant prostate cancers through in vitro drug response modeling

W Zhang, AM Lee, S Jena, Y Huang… - Proceedings of the …, 2023 - National Acad Sciences
Prostate cancer (PC) is the most frequently diagnosed malignancy and a leading cause of
cancer deaths in US men. Many PC cases metastasize and develop resistance to systemic …

Computational drug discovery for castration-resistant prostate cancers through in vitro drug response modeling

W Zhang, AM Lee, S Jena, Y Huang, Y Ho… - Proceedings of the …, 2023 - experts.umn.edu
Prostate cancer (PC) is the most frequently diagnosed malignancy and a leading cause of
cancer deaths in US men. Many PC cases metastasize and develop resistance to systemic …

Computational drug discovery for castration-resistant prostate cancers through in vitro drug response modeling

W Zhang, AM Lee, S Jena, Y Huang… - Proceedings of the …, 2023 - ui.adsabs.harvard.edu
This research develops a computational framework to quickly propose drugs with potential
clinical impact for CRPC patients that are resistant to hormonal therapies. Furthermore, we …

[HTML][HTML] Computational drug discovery for castration-resistant prostate cancers through in vitro drug response modeling

W Zhang, AM Lee, S Jena, Y Huang, Y Ho… - Proceedings of the …, 2023 - ncbi.nlm.nih.gov
Results Overall Computational Drug Nomination Workflow. The overall design of our
computational method is shown in Fig. 1. Our framework comprises two stand-alone steps …

Computational drug discovery for castration-resistant prostate cancers through in vitro drug response modeling

W Zhang, AM Lee, S Jena, Y Huang… - Proceedings of the …, 2023 - pubmed.ncbi.nlm.nih.gov
Prostate cancer (PC) is the most frequently diagnosed malignancy and a leading cause of
cancer deaths in US men. Many PC cases metastasize and develop resistance to systemic …

[PDF][PDF] Computational drug discovery for castration-resistant prostate cancers through in vitro drug response modeling

W Zhanga, AM Leeb, S Jenab, Y Huangb, Y Hoc… - 2023 - pdfs.semanticscholar.org
Results Overall Computational Drug Nomination Workflow. The overall design of our
computational method is shown in Fig. 1. Our framework comprises two stand-alone steps …

Computational drug discovery for castration-resistant prostate cancers through in vitro drug response modeling.

W Zhang, AM Lee, S Jena, Y Huang, Y Ho… - Proceedings of the …, 2023 - europepmc.org
Results Overall Computational Drug Nomination Workflow. The overall design of our
computational method is shown in Fig. 1. Our framework comprises two stand-alone steps …