A vasculature niche orchestrates stromal cell phenotype through PDGF signaling: Importance in human fibrotic disease

TB Layton, L Williams, N Yang… - Proceedings of the …, 2022 - National Acad Sciences
Fibrosis is characterized by excessive matrix protein accumulation and contributes to
significant morbidity and mortality in the Western world. The relative lack of effective …

A vasculature niche orchestrates stromal cell phenotype through PDGF signaling: Importance in human fibrotic disease

TB Layton, L Williams, N Yang… - Proceedings of the …, 2022 - pubmed.ncbi.nlm.nih.gov
SignificanceTissue fibrotic diseases, for example of the liver and lung, represent a huge
unmet medical need. In this study, using single-cell RNA sequencing, cytometry by time of …

[HTML][HTML] A vasculature niche orchestrates stromal cell phenotype through PDGF signaling: Importance in human fibrotic disease

TB Layton, L Williams, N Yang, M Zhang… - Proceedings of the …, 2022 - ncbi.nlm.nih.gov
Results Single-Cell Atlas of the Vascular Niche in Human Fibrosis. To investigate
vasculature heterogeneity during human fibrosis, we first performed paired single-cell RNA …

A vasculature niche orchestrates stromal cell phenotype through PDGF signaling: Importance in human fibrotic disease.

TB Layton, L Williams, N Yang, M Zhang… - Proceedings of the …, 2022 - europepmc.org
SignificanceTissue fibrotic diseases, for example of the liver and lung, represent a huge
unmet medical need. In this study, using single-cell RNA sequencing, cytometry by time of …

A vasculature niche orchestrates stromal cell phenotype through PDGF signaling: Importance in human fibrotic disease

TB Layton, L Williams, N Yang… - Proceedings of the …, 2022 - ui.adsabs.harvard.edu
Tissue fibrotic diseases, for example of the liver and lung, represent a huge unmet medical
need. In this study, using single-cell RNA sequencing, cytometry by time of flight (CyTOF) …

A vasculature niche orchestrates stromal cell phenotype through PDGF signaling: importance in human fibrotic disease

TB Layton, L Williams, N Yang, M Zhang… - Proceedings of the …, 2022 - ora.ox.ac.uk
Fibrosis is characterized by excessive matrix protein accumulation and contributes to
significant morbidity and mortality in the Western world. The relative lack of effective …

A vasculature niche orchestrates stromal cell phenotype through PDGF signaling: Importance in human fibrotic disease.

TB Layton, L Williams, N Yang, M Zhang… - Proceedings of the …, 2022 - europepmc.org
Results Single-Cell Atlas of the Vascular Niche in Human Fibrosis. To investigate
vasculature heterogeneity during human fibrosis, we first performed paired single-cell RNA …