Cas9 off-target binding to the promoter of bacterial genes leads to silencing and toxicity

W Rostain, T Grebert, D Vyhovskyi… - Nucleic Acids …, 2023 - academic.oup.com
Genetic tools derived from the Cas9 RNA-guided nuclease are providing essential
capabilities to study and engineer bacteria. While the importance of off-target effects was …

Cas9 off-target binding to the promoter of bacterial genes leads to silencing and toxicity

W Rostain, T Grebert, D Vyhovskyi… - Nucleic acids …, 2023 - pubmed.ncbi.nlm.nih.gov
Genetic tools derived from the Cas9 RNA-guided nuclease are providing essential
capabilities to study and engineer bacteria. While the importance of off-target effects was …

Cas9 off-target binding to the promoter of bacterial genes leads to silencing and toxicity

W Rostain, T Grebert, D Vyhovskyi… - Nucleic Acids …, 2023 - pasteur.hal.science
Genetic tools derived from the Cas9 RNA-guided nuclease are providing essential
capabilities to study and engineer bacteria. While the importance of off-target effects was …

[HTML][HTML] Cas9 off-target binding to the promoter of bacterial genes leads to silencing and toxicity

W Rostain, T Grebert, D Vyhovskyi… - Nucleic Acids …, 2023 - ncbi.nlm.nih.gov
Genetic tools derived from the Cas9 RNA-guided nuclease are providing essential
capabilities to study and engineer bacteria. While the importance of off-target effects was …

[PDF][PDF] Cas9 off-target binding to the promoter of bacterial genes leads to silencing and toxicity

W Rostain, T Grebert, D Vyhovskyi… - Nucleic Acids …, 2023 - academic.oup.com
Genetic tools derived from the Cas9 RNA-guided nuclease are providing essential
capabilities to study and engineer bacteria. While the importance of off-target effects was …

[PDF][PDF] Cas9 off-target binding to the promoter of bacterial genes leads to silencing and toxicity

W Rostain, T Grebert, D Vyhovskyi… - Nucleic Acids …, 2023 - pdfs.semanticscholar.org
Genetic tools derived from the Cas9 RNA-guided nuclease are providing essential
capabilities to study and engineer bacteria. While the importance of offtarget effects was …

[PDF][PDF] Cas9 off-target binding to the promoter of bacterial genes leads to silencing and toxicity

W Rostain, T Grebert, D Vyhovskyi… - Nucleic Acids …, 2023 - scholar.archive.org
Genetic tools derived from the Cas9 RNA-guided nuclease are providing essential
capabilities to study and engineer bacteria. While the importance of offtarget effects was …

Cas9 off-target binding to the promoter of bacterial genes leads to silencing and toxicity.

W Rostain, T Grebert, D Vyhovskyi, PT Pizarro… - Nucleic Acids …, 2023 - europepmc.org
Genetic tools derived from the Cas9 RNA-guided nuclease are providing essential
capabilities to study and engineer bacteria. While the importance of off-target effects was …

Cas9 off-target binding to the promoter of bacterial genes leads to silencing and toxicity.

W Rostain, T Grebert, D Vyhovskyi, PT Pizarro… - Nucleic Acids …, 2023 - europepmc.org
Genetic tools derived from the Cas9 RNA-guided nuclease are providing essential
capabilities to study and engineer bacteria. While the importance of off-target effects was …