Interaction of modified oligonucleotides with nuclear proteins, formation of novel nuclear structures and sequence-independent effects on RNA processing

LL Flynn, R Li, MT Aung-Htut, IL Pitout, JAL Cooper… - BioRxiv, 2018 - biorxiv.org
Oligonucleotides and nucleic acid analogues that alter gene expression are showing
therapeutic promise for selected human diseases. The modification of synthetic nucleic …

[PDF][PDF] Interaction of modified oligonucleotides with nuclear proteins, formation of novel nuclear structures and sequence-independent effects on RNA processing

LL Flynn, R Li, MT Aung-Htut, IL Pitout, J Cooper… - researchgate.net
Antisense oligonucleotide drugs are a class of therapeutics designed to alter gene
expression and function, and are reported to have delivered therapeutic benefit to spinal …

Interaction of modified oligonucleotides with nuclear proteins, formation of novel nuclear structures and sequence-independent effects on RNA processing

LL Flynn, R Li, MT Aung-Htut, IL Pitout, JAL Cooper… - 2018 - europepmc.org
Oligonucleotides and nucleic acid analogues that alter gene expression are showing
therapeutic promise for selected human diseases. The modification of synthetic nucleic …